Palladium(II)-Catalyzed Transformation of 3-Alkylbenzofurans to [2,3′-Bibenzofuran]-2′(3′H)-ones: Oxidative Dimerization of 3-Alkylbenzofurans

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• 作者：Beom Shin Cho ; Young Keun Chung
• 刊名：Journal of Organic Chemistry
• 出版年：2017
• 出版时间：February 17, 2017
• 年：2017
• 卷：82
• 期：4
• 页码：2237-2242
• 全文大小：405K
• ISSN：1520-6904

文摘

An unprecedented oxidative dimerization by palladium catalysis has been developed using PhI(OPiv)₂ as a by-standing oxidant. This provides a facile method for the synthesis of quaternary 2,3′-bibenzofuran-2′(3′)-ones from readily accessible substrates. A plausible mechanism involving a Pd(II)–Pd(IV) catalytic cycle is proposed; a trace amount of water is required for subsequent oxidation.