Palladium-Catalyzed Domino Heck/Aryne Carbopalladation/C–H Functionalization: Synthesis of Heterocycle-Fused 9,10-Dihydrophenanthrenes

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• 作者：Tuanli YaoDan He
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：February 17, 2017
• 年：2017
• 卷：19
• 期：4
• 页码：842-845
• 全文大小：404K
• ISSN：1523-7052

文摘

A novel palladium-catalyzed domino Heck/aryne carbopalladation/C–H functionalization reaction using in situ generated arynes has been developed in which three new C–C bonds and a carbon quaternary center are formed. This methodology affords moderate to excellent yields of heterocycle-fused 9,10-dihydrophenanthrenes.