Copper-Catalyzed Stereodefined Construction of Acrylic Acid Derivatives from Terminal Alkynes via CO2 Insertion

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• 作者：Kenta Kuge ; Ying Luo ; Yuki Fujita ; Yasuyuki Mori ; Gen Onodera ; Masanari Kimura
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：February 17, 2017
• 年：2017
• 卷：19
• 期：4
• 页码：854-857
• 全文大小：282K
• ISSN：1523-7052

文摘

IPrCuCl catalyzes the CO₂ insertion reaction undergone by a dialkylvinylborane intermediate derived from alkynyltrialkylborate by a 1,2-alkyl group migration to afford α-alkyl acrylic acids with excellent regio- and stereoselectivities.