Diastereoselective Electrophilic α-Hydroxyamination of N-tert-Butanesulfinyl Imidates

详细信息    查看全文

• 作者：Peng-Ju Ma ; Hui Liu ; Chong-Dao LuYan-Jun Xu
• 刊名：Organic Letters
• 出版年：2017
• 出版时间：February 3, 2017
• 年：2017
• 卷：19
• 期：3
• 页码：670-673
• 全文大小：318K
• ISSN：1523-7052

文摘

Diastereoselective α-hydroxyamination of N-tert-butanesulfinyl imidates using nitrosoarenes is reported. A catalytic amount of base effectively promotes the hydroxyamination reaction of α-aryl-substituted imidates, and the resulting α-hydroxyamino imidates can be transformed into a range of synthetically useful intermediates.