Contamination of commercially available seafood by key diarrhetic shellfish poisons along the coast of China

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• 作者：Chao Lin (1)
  Zeng-Shan Liu (1)
  Cai-Yun Tan (2)
  Yi-Ping Guo (2)
  Lin Li (1)
  Hong-Lin Ren (1)
  Yan-Song Li (1)
  Pan Hu (1)
  Sheng Gong (1)
  Yu Zhou (1)
  Shi-Ying Lu (1)
  
  1. Key Laboratory of Zoonosis Research ; Ministry of Education ; Institute of Zoonosis ; College of Veterinary Medicine ; Jilin University ; Changchun ; 130062 ; People鈥檚 Republic of China
  2. Dalian Zhongxin Testing Technology ; LLC ; Dalian ; 116045 ; People鈥檚 Republic of China
  
• 关键词：Okadaic acid (OA) ; Dinophysistoxin ; 1 (DTX ; 1) ; Contamination ; Detection ; Commercially available seafood
• 刊名：Environmental Science and Pollution Research
• 出版年：2015
• 出版时间：January 2015
• 年：2015
• 卷：22
• 期：2
• 页码：1545-1553
• 全文大小：571 KB
• 参考文献：1. Boland MP, Taylor MF, Holmes CF (1993) Identification and characterisation of a type-1 protein phosphatase from the okadaic acid-producing marine dinoflagellate Prorocentrum lima. FEBS Lett 334:13鈥?7 CrossRef
  2. Chen T, Xu X, Wei J, Chen J, MIU R, Huang L, Zhou X, FU Y, Yan R, Wang Z, Liu B, He F (2013) Food-borne disease outbreak of diarrhetic shellfish poisoning due to toxic mussel consumption: the first recorded outbreak in China. PLoS One 8:e65049 CrossRef
  3. Christian B, Luckas B (2008) Determination of marine biotoxins relevant for regulations: from the mouse bioassay to coupled LC-MS methods. Anal Bioanal Chem 391:117鈥?34 CrossRef
  4. Cordier S, Monfort C, Miossec L, Richardson S, Belin C (2000) Ecological analysis of digestive cancer mortality related to contamination by diarrhetic shellfish poisoning toxins along the coasts of France. Environ Res 84:145鈥?50 CrossRef
  5. Dickey RW, Bobzin SC, Faulkner DJ, Bencsath FA, Andrzejewski D (1990) Identification of okadaic acid from a Caribbean dinoflagellate, Prorocentrum concavum. Toxicon 28:371鈥?77 CrossRef
  6. Hallegraeff GM, Anderson DM, Cembella AD (eds) (1995) Manual on harmful marine microalgae. UNESCO, Paris
  7. Huang X, Lei F and Jiang TJ (2013) The pattern of diarrhetic shellfish poisoning in the coast of the east China Sea and the South China Sea. Journal of Jinan University(Nature Science). 34
  8. James KJ, Carey B, O鈥橦alloran J, Van Pelt FN, Skrabakova Z (2010) Shellfish toxicity: human health implications of marine algal toxins. Epidemiol Infect 138:927鈥?40 CrossRef
  9. Kacem I, Hajjem B, Boua Cha N (2009) First evidence of okadaic acid in Mytilus galloprovincialis mussels, collected in a Mediterranean Lagoon. Tunisia Bull Environ Contam Toxicol 82:660鈥?64 CrossRef
  10. Kat M (1983) Diarrhetic mussel poisoning in the Netherlands related to the dinoflagellate Dinophysis acuminata. Antonie Van Leeuwenhoek 49:417鈥?27
  11. Lee KJ, Mok JS, Song KC, Yu H, Lee DS, Jung JH, Kim JH (2012) First detection and seasonal variation of lipophilic toxins okadaic acid, dinophysistoxin-1, and yessotoxin in Korean gastropods. J Food Prot 75:2000鈥?006 CrossRef
  12. Li A, Ma J, Cao J and Mccarron P (2012) Toxins in mussels (<i > Mytilus galloprovincialis</i>) associated with diarrhetic shellfish poisoning episodes in China. Toxicon: official journal of the International Society on Toxinology
  13. Liu N, Pang GW (1999) Survey and analysis of shellfish contaminated by okadaic acid in Liaodong Bay tide polluted waters. China Public Health 15:209鈥?10
  14. Louppis AP, Badeka AV, Katikou P, Paleologos EK, Kontominas MG (2010) Determination of okadaic acid, dinophysistoxin-1 and related esters in Greek mussels using HPLC with fluorometric detection, LC-MS/MS and mouse bioassay. Toxicon 55:724鈥?33 CrossRef
  15. Lu SY, Zhou Y, Li YS, Lin C, Meng XM, Yan DM, Li ZH, Yu SY, Liu ZS, Ren HL (2011) Production of monoclonal antibody and application in indirect competitive ELISA for detecting okadaic acid and dinophytoxin-1 in seafood. Environ Sci Pollut Res Int 19:2619鈥?626 CrossRef
  16. Lu SY, Lin C, Li YS, Zhou Y, Meng XM, Yu SY, Li ZH, Li L, Ren HL, Liu ZS (2012) A screening lateral flow immunochromatographic assay for on-site detection of okadaic acid in shellfish products. Anal Biochem 422:59鈥?5 CrossRef
  17. Madigan TL, Lee KG, Padula DJ, Mcnabb P, Pointon AM (2006) Diarrhetic shellfish poisoning (DSP) toxins in South Australian shellfish. Harmful Algae 5:119鈥?23 CrossRef
  18. Manerio E, Rodas VL, Costas E, Hernandez JM (2008) Shellfish consumption: a major risk factor for colorectal cancer. Med Hypotheses 70:409鈥?12 CrossRef
  19. Morton SL, Moeller PD, Young KA, Lanoue B (1998) Okadaic acid production from the marine dinoflagellate Prorocentrum belizeanum Faust isolated from the Belizean coral reef ecosystem. Toxicon 36:201鈥?06 CrossRef
  20. Mouratidou T, Kaniou-Grigoriadou I, Samara C, Kouimtzis T (2006) Detection of the marine toxin okadaic acid in mussels during a diarrhetic shellfish poisoning (DSP) episode in Thermaikos Gulf, Greece, using biological, chemical and immunological methods. Sci Total Environ 366:894鈥?04 CrossRef
  21. Prassopoulou E, Katikou P, Georgantelis D, Kyritsakis A (2009) Detection of okadaic acid and related esters in mussels during diarrhetic shellfish poisoning (DSP) episodes in Greece using the mouse bioassay, the PP2A inhibition assay and HPLC with fluorimetric detection. Toxicon 53:214鈥?27 CrossRef
  22. Rong Hu T.-J.J (2013) Analysis on diarrhetic shellfish poisoning in bivalve collected from different coastal areas in Hainan Island. J Jinan Univ ( Natural Sci). 34
  23. Rundberget T, Sandvik M, Larsen K, Pizarro GM, Reguera B, Castberg T, Gustad E, Loader JI, Rise F, Wilkins AL, Miles CO (2007) Extraction of microalgal toxins by large-scale pumping of seawater in Spain and Norway, and isolation of okadaic acid and dinophysistoxin-2. Toxicon 50:960鈥?70 CrossRef
  24. Sassolas A, Hayat A, Catanante G, Marty JL (2013) Detection of the marine toxin okadaic acid: assessing seafood safety. Talanta 105:306鈥?16 CrossRef
  25. Taylor M, Mcintyre L, Ritson M, Stone J, Bronson R, Bitzikos O, Rourke W, Galanis E, Team OI (2013) Outbreak of diarrhetic shellfish poisoning associated with mussels, british columbia. Canada Mar Drugs 11:1669鈥?676 CrossRef
  26. Torgersen T, Aasen J, Aune T (2005) Diarrhetic shellfish poisoning by okadaic acid esters from brown crabs (Cancer pagurus) in Norway. Toxicon Off J Int Soc Toxinology 46:572鈥?78 CrossRef
  27. Trainer VL, Moore L, Bill BD, Adams NG, Harrington N, Borchert J, Da Silva DA, Eberhart B-TL (2013) Diarrhetic shellfish toxins and other lipophilic toxins of human health concern in Washington State. Mar Drugs 11:1815鈥?835 CrossRef
  28. Viviani R (1991) Eutrophication, marine biotoxins, human health. Sci Total Environ. 631-662
  29. Webb JL, Vandenbor J, Pirie B, Robinson SMC, Cross SF, Jones SRM, Pearce CM (2013) Effects of temperature, diet, and bivalve size on the ingestion of sea lice (Lepeophtheirus salmonis) larvae by various filter-feeding shellfish. Aquaculture 406鈥?07:9鈥?7 CrossRef
  30. Yang WD, Peng XC, Liu JS, Peng ZY (2005) Review on research of diarrhetic shellfish poisoning. Mar Sci 29:66鈥?2
  31. Yang ML, Jia XP, Lin Q, Lv XY, CAI WG (2009) Diarrhetic shellfish poison in oyster in major culture waters in South China Sea. Mar Environ Sci 28:410鈥?10
  32. Zhang SG, Zou Q, Chen L, Hao JZ (2011) Analysis of diarrhetic shellfish poisoning in Zhe Nan Waters. Mar Sci 35:44鈥?7
  33. Zhao XF, Ji R (2006) Comparative study on the management and control of diarrhetic shellfish poisons. China Trop Med 6:350鈥?54
  
• 刊物类别：Earth and Environmental Science
• 刊物主题：Environment
  Environment
  Atmospheric Protection, Air Quality Control and Air Pollution
  Waste Water Technology, Water Pollution Control, Water Management and Aquatic Pollution
  Industrial Pollution Prevention
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1614-7499

文摘

With the increasing number of outbreaks of food-borne diseases caused by okadaic acid (OA) and its analogue dinophysistoxin-1 (DTX-1), two key diarrhetic shellfish poison (DSP) toxins, OA and DTX-1, have become a serious threat to public health and have attracted significant public attention in China. The aim of our study was to monitor OA and DTX-1 contamination in commercially available seafood and to provide references for tracking these toxins and preventing disease outbreaks. From 2010 to 2012, 40 species were collected from six coastal cities of four inland seas in China. An enzyme-linked immunosorbent assay (ELISA) and a lateral flow immunochromatographic (LFIC) test strip were used to analyse the samples, and the results were further confirmed using a commercially available ELISA kit. The monitoring results indicated that 23 of 40 species were positive for contamination. In addition, 14 of the positive species were determined to be inedible because the content of OA and DTX-1 was above the regulatory limit. Simultaneously, we verified that the digestive glands of shellfish tended to accumulate toxin, in contrast to the flesh. The highest concentrations of OA and DTX-1 were recorded in Scapharca broughtonii, which was collected from Qing Dao, in relation to the other analysed species. Moreover, the Arca family as well as Mytilus galloprovincialis were severely contaminated by OA and its analogue. The above results indicate that some of the commercially available seafood from the coastal cities in China may be inedible due to serious marine toxin contamination. The results of this study might play an important role in protecting consumer health and safety screening of marine products.