Current status and future role of brain PET/MRI in clinical and research settings

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• 作者：P. Werner (1)
  H. Barthel (1)
  A. Drzezga (2)
  O. Sabri (1)
  
  1. Department of Nuclear Medicine ; University Hospital Leipzig ; Liebigstr. 18 ; 04103 ; Leipzig ; Germany
  2. Department of Nuclear Medicine ; University Hospital Cologne ; 50937 ; K枚ln ; Germany
  
• 关键词：PET/MRI ; Dementia ; Brain tumours ; Stroke ; Functional MRI ; Molecular imaging
• 刊名：European Journal of Nuclear Medicine and Molecular Imaging
• 出版年：2015
• 出版时间：March 2015
• 年：2015
• 卷：42
• 期：3
• 页码：512-526
• 全文大小：7,185 KB
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• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Nuclear Medicine
  Imaging and Radiology
  Orthopedics
  Cardiology
  Oncology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1619-7089

文摘

Hybrid PET/MRI systematically offers a complementary combination of two modalities that has often proven itself superior to the single modality approach in the diagnostic work-up of many neurological and psychiatric diseases. Emerging PET tracers, technical advances in multiparametric MRI and obvious workflow advantages may lead to a significant improvement in the diagnosis of dementia disorders, neurooncological diseases, epilepsy and neurovascular diseases using PET/MRI. Moreover, simultaneous PET/MRI is well suited to complex studies of brain function in which fast fluctuations of brain signals (e.g. related to task processing or in response to pharmacological interventions) need to be monitored on multiple levels. Initial simultaneous studies have already demonstrated that these complementary measures of brain function can provide new insights into the functional and structural organization of the brain.