Construction and application of the robust Youden plot in an EQA program

详细信息    查看全文

• 作者：Qi Zhou ; Jihong Hu ; Xiaopeng Li ; Shaonan Li…
• 关键词：Data distribution ; EQA ; Robust statistical method ; Robust Youden plot ; Robust z ; score
• 刊名：Accreditation and Quality Assurance: Journal for Quality, Comparability and Reliability in Chemical Measurement
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：20
• 期：3
• 页码：195-201
• 全文大小：339 KB
• 参考文献：1.Howerton D, Krolak JM, Manasterski A, Handsfield JH (2010) Proficiency testing performance in US laboratories. Arch Pathol Lab Med 134:751-58
  2.Youden WJ (1959) Graphical diagnosis of inter-laboratory test results. Ind Qual Control 15(11):133-37
  3.Mandel J, Lashof TW (1974) Interpretation and generalization of Youden’s two-sample diagram. J Qual Technol 6:22-6
  4.Zhou Q, Li SN, Li XP, Wang W, Wang ZG (2006) Detection of outliers and establishment of targets in external quality assessment programs. Clin Chim Acta 372(1-):94-7
  5.ISO13528 (2005) Statistical methods for use in proficiency testing by inter-laboratory comparisons. ISO, Geneva
  6.Guide to NATA proficiency testing (2004) National Association of Testing Authorities. Australia ACN 004 379 748 page-18/line-23 http://?www.?farmacia.?ufmg.?br/?lato/?NATAproficiency%20-20?testing%20?guide.?pdf
  7.Zhou Q, Xu JP, Xie W, Li SN, Li XP (2011) Use of robust ZB and ZW to evaluate proficiency testing data. Clin Chim Acta 412(11-2):936-39View Article
  8.Sanyal D, Rani A (2009) Proficiency test for chemical laboratories for the analysis of a pesticide in a formulated product: inter-laboratory study. J AOAC Int 92(1):271-78
  9.Kallner A (2014) Laboratory statistics, handbook of formulas and terms. Elsevier, Amsterdam
  
• 作者单位：Qi Zhou (1)
  Jihong Hu (1)
  Xiaopeng Li (1)
  Shaonan Li (1)
  Zhenxiang Gao (1)
  Jianping Xu (1)
  Wei Xie (1)
  
  1. National Center for Clinical Laboratories, Beijing Hospital, 1. Da Hua Road, 100730, Beijing, People’s Republic of China
  
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Analytical Chemistry
  Food Science
  Biochemistry
  Commercial Law
  Monitoring, Environmental Analysis and Environmental Ecotoxicology
  Marketing
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1432-0517

文摘

The Youden plot is a method of graphical data analysis used in inter-laboratory comparisons. The confidence ellipse of a traditional Youden plot can be distorted by non-normally distributed data. In this study, a robust Youden plot is constructed based on robust statistical parameters since these are scarcely affected by non-normally distributed data and this approach is applied in an external quality assessment (EQA) program. We consider the robust between-laboratory z-scores (z _b,i ) and within-laboratory z-scores (z _w,i ) obtained by the participants of EQA schemes regarding glucose concentration measurement results and their locations relative to the confidence ellipse in a robust Youden plot. It turned out that 98.1?% of the acceptable results (|z _b,i |?≤? as well as |z _w,i |?≤?) are located inside the ellipse and that 92.9?% of questionable results with z-scores between 2 and 3 are located on or near the ellipse; while all the unacceptable results (at least one z-score equal to or larger than 3) are located outside the ellipse. These results indicate that, in an EQA program, it is reasonable to choose robust statistical techniques to construct the Youden plot and robust z-scores, in order to illustrate and assess the EQA data.