Factors affecting survival of medulloblastoma in children: the changing concept of management

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• 作者：Tai-Tong Wong ; Yen-Lin Liu ; Donald Ming-Tak Ho ; Kai-Ping Chang…
• 刊名：Child's Nervous System
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：31
• 期：10
• 页码：1687-1698
• 全文大小：7,305 KB
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• 作者单位：Tai-Tong Wong (1) (13) (6)
  Yen-Lin Liu (2) (3)
  Donald Ming-Tak Ho (4)
  Kai-Ping Chang (5)
  Muh-Lii Liang (6)
  Hsin-Hung Chen (6)
  Yi-Yen Lee (6)
  Feng-Chi Chang (7)
  Shih-Chieh Lin (4)
  Ting-Rong Hsu (5)
  Kuo-Wei Chen (8)
  Wei-Kang Kwang (9)
  Wu-Yu Hou (10)
  Chung-Yih Wang (11)
  Sang-Hue Yen (1)
  Wan-You Guo (6)
  Yi-Wei Chen (12)
  
  1. Department of Neurosurgery, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan
  13. Pediatric Neurosurgery, Department of Neurosurgery, Taipei Medical University Hospital, 252 Wuxing St, Taipei, 11031, Taiwan
  6. Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
  2. Department of Pediatrics, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan
  3. National Taiwan University and Academia Sinica, Taipei, Taiwan
  4. Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
  5. Department of Pediatrics, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
  7. Department of Radiology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, Taipei, Taiwan
  8. Department of Internal Medicine, Cheng Hsin General Hospital, Taipei, Taiwan
  9. Department of Pathology, Cheng Hsin General Hospital, Taipei, Taiwan
  10. Department of Radiology, Chen Hsin General Hospital, Taipei, Taiwan
  11. Department of Radiation Oncology, Cheng Hsin General Hospital, Taipei, Taiwan
  12. Department of Oncology, Taipei Veterans General Hospital and National Yang Ming University, School of Medicine, 201 Sec 2 Shi Pai Rd, Taipei, 11217, Taiwan
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Neurosurgery
  Neurosciences
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1433-0350

文摘

Medulloblastoma (MB) is a type of malignant tumor arising only in the cerebellum that was first defined by Cushing and Bailey in 1920s. In this review paper, we trace the evolution of risk stratification and the correlated changing concept of management in the past years. Outcome analysis of the hospital series of the Taipei Veterans General Hospital, Cheng Hsin General Hospital, and Taipei Medical University Hospital was performed to correlate prognostic indicators with reported studies. The purpose is to provide clues for age-specific and risk-adjusted optimal, effective, but beneficial and protective treatment strategies of these tumors in children. Tai-Tong Wong, Yen-Lin Liu, Donald Ming-Tak Ho and Kai-Ping Chang contributed equally to this work.