Toll-like receptor-associated keratitis and strategies for its management

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• 作者：Amandeep Kaur ; Vijay Kumar ; Simranjeet Singh ; Joginder Singh ; Niraj Upadhyay&#8230
• 关键词：Toll ; like receptor ; Keratitis ; Infection ; Treatment ; Cytokines
• 刊名：3 Biotech
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：5
• 期：5
• 页码：611-619
• 全文大小：753 KB
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• 作者单位：Amandeep Kaur (2)
  Vijay Kumar (1)
  Simranjeet Singh (2)
  Joginder Singh (1)
  Niraj Upadhyay (1)
  Shivika Datta (3)
  Sourav Singla (2)
  Virender Kumar (1)
  
  2. Department of Biotechnology, Lovely Professional University, Phagwara, 144411, Punjab, India
  1. Department of Chemistry, Lovely Professional University, Phagwara, 144411, Punjab, India
  3. Department of Zoology, Lovely Professional University, Phagwara, 144411, Punjab, India
  
• 刊物主题：Biotechnology; Agriculture; Cancer Research; Bioinformatics; Stem Cells; Biomaterials;
• 出版者：Springer Berlin Heidelberg
• ISSN：2190-5738

文摘

Keratitis is an inflammatory condition, characterized by involvement of corneal tissues. Most recurrent challenge of keratitis is infection. Bacteria, virus, fungus and parasitic organism have potential to cause infection. TLR are an important class of protein which has a major role in innate immune response to combat with pathogens. In last past years, extensive research efforts have provided considerable abundance information regarding the role of TLR in various types of keratitis. This paper focuses to review the recent literature illustrating amoebic, bacterial, fungal and viral keratitis associated with Toll-like receptor molecules and summarize existing thoughts on pathogenesis and treatment besides future probabilities for prevention against TLR-associated keratitis. Keywords Toll-like receptor Keratitis Infection Treatment Cytokines