Genetic screening in sudden cardiac death in the young can save future lives

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• 作者：Eva-Lena Stattin ; Ida Maria Westin…
• 关键词：Sudden unexplained death ; Sudden cardiac death ; Molecular autopsy ; Long QT syndrome ; Catecholaminergic polymorphic ventricular tachycardia
• 刊名：International Journal of Legal Medicine
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：130
• 期：1
• 页码：59-66
• 全文大小：327 KB
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• 作者单位：Eva-Lena Stattin (1)
  Ida Maria Westin (1)
  Kristina Cederquist (1)
  Jenni Jonasson (1)
  Björn-Anders Jonsson (1)
  Stellan Mörner (2)
  Anna Norberg (1)
  Peter Krantz (3)
  Aase Wisten (4)
  
  1. Department of Medical Biosciences, Medical and Clinical Genetics, Umeå University, Umeå, Sweden
  2. Heart Centre and Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden
  3. Department of Forensic Medicine, Lund University, Lund, Sweden
  4. Department of Internal Medicine, Sunderby Hospital, Luleå, Sweden
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Forensic Medicine
  Medical Law
  Medicine/Public Health, general
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1437-1596

文摘

Background Autopsy of sudden cardiac death (SCD) in the young shows a structurally and histologically normal heart in about one third of cases. Sudden death in these cases is believed to be attributed in a high percentage to inherited arrhythmogenic diseases. The purpose of this study was to investigate the value of performing post-mortem genetic analysis for autopsy-negative sudden unexplained death (SUD) in 1 to 35 year olds.