CD146+ mesenchymal stem cells display greater therapeutic potential than CD146– cells for treating collagen-induced arthritis in mice

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• 作者：Cheng-Chi Wu ; Fei-Lan Liu ; Huey-Kang Sytwu ; Chang-Youh Tsai…
• 关键词：CD146 ; Mesenchymal stem cells ; Collagen ; induced arthritis
• 刊名：Stem Cell Research & Therapy
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：7
• 期：1
• 全文大小：2,291 KB
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• 作者单位：Cheng-Chi Wu (1) (2)
  Fei-Lan Liu (2)
  Huey-Kang Sytwu (1)
  Chang-Youh Tsai (2)
  Deh-Ming Chang (1) (2)
  
  1. Graduate Institute of Life Sciences, National Defense Medical Center, No.161, Sec. 6, Minquan E. Rd., Neihu Dist., Taipei, 114, Taiwan, Republic of China
  2. Taipei Veterans General Hospital, No.201, Sec. 2, Shipai Rd., Beitou District., Taipei, 112, Taiwan, Republic of China
  
• 刊物主题：Stem Cells; Cell Biology;
• 出版者：BioMed Central
• ISSN：1757-6512

文摘

Background The characteristics and therapeutic potential of subtypes of mesenchymal stem cells (MSCs) are largely unknown. In this study, CD146+ and CD146– MSCs were separated from human umbilical cords, and their effects on regulatory T cells (Tregs), Th17 cells, chondrogenesis, and osteogenesis were investigated.