Characterization of various cell lines from different ampullary cancer subtypes and cancer associated fibroblast-mediated responses

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• 作者：Zon Weng Lai ; Louisa Bolm ; Hannah Fuellgraf ; Martin L. Biniossek…
• 关键词：Ampullary adenocarcinoma ; Fibroblast ; Differentiation ; Intestinal ; Pancreatobiliary ; Dysplastic ; Cell proliferation ; Cell invasion
• 刊名：BMC Cancer
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：16
• 期：1
• 全文大小：3,623 KB
• 刊物主题：Cancer Research; Oncology; Stem Cells; Animal Models; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2407

文摘

Background Ampullary cancer is a relatively rare form of cancer and usually treated by pancreatoduodenectomy, followed by adjuvant therapy. The intestinal subtype is associated with markedly improved prognosis after resection. At present, only few cell lines are available for in vitro studies of ampullary cancer and they have not been collectively characterized.