Integrated analysis of gene expression and methylation profiles of 48 candidate genes in breast cancer patients

详细信息    查看全文

• 作者：Zibo Li ; Jianfu Heng ; Jinhua Yan ; Xinwu Guo…
• 关键词：Breast cancer ; Methylation ; Gene expression ; Microfludic PCR ; Next ; generation sequencing
• 刊名：Breast Cancer Research and Treatment
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：160
• 期：2
• 页码：371-383
• 全文大小：438 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  
• 出版者：Springer Netherlands
• ISSN：1573-7217
• 卷排序：160

文摘

PurposeGene-specific methylation and expression have shown biological and clinical importance for breast cancer diagnosis and prognosis. Integrated analysis of gene methylation and gene expression may identify genes associated with biology mechanism and clinical outcome of breast cancer and aid in clinical management.