Silica-Based Phenyl and Octyl Bifunctional Imidazolium as a New Mixed-Mode Stationary Phase for Reversed-Phase and Anion-Exchange Chromatography

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• 作者：Qiong Jiang ; Wenjie Zhao ; Hongdeng Qiu ; Shusheng Zhang
• 关键词：Ionic liquids ; Silica ; Mixed ; mode stationary phase ; Reversed ; phase chromatography ; Anion ; exchange chromatography
• 刊名：Chromatographia
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：79
• 期：21-22
• 页码：1437-1443
• 全文大小：641 KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry
  Analytical Chemistry
  Organic Chemistry
  Pharmacy
  Biochemistry
  Plant Sciences
  Measurement Science and Instrumentation
  
• 出版者：Vieweg Verlag
• ISSN：1612-1112
• 卷排序：79

文摘

In this study, octylbenzimidazolium-modified silica (BeImC8-Sil) was prepared by covalent attachment of 1-octylbenzimidazole to γ-chloropropyl silica. The synthesized materials were characterized by the elemental analysis, IR spectrum, and thermogravimetric analysis. Due to the introduction of phenyl and octyl groups on the quaternary imidazolium, the developed BeImC8-Sil column can function via both reversed-phase and anion-exchange retention mechanisms. The chromatographic properties of the synthesized material were investigated by the separations of polycyclic aromatic hydrocarbons, mono-substituted derivatives of benzene, anilines, and phenols, revealing the existence of multiple interactions, including hydrogen bonding, π–π stacking, electrostatic forces, and hydrophobic interactions in reversed-phase mode; inorganic and organic anions were also separated mainly through anion-exchange interaction. The proposed BeImC8-Sil is a promising mixed-mode stationary phase for the separation of complex samples in high-performance liquid chromatography.