Preoperative Neutrophil-Lymphocyte and Lymphocyte-Monocyte Ratios Reflect Immune Cell Population Rearrangement in Resectable Pancreatic Cancer

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• 作者：Marek Sierzega PhD ; Marzena Lenart PhD…
• 刊名：Annals of Surgical Oncology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：24
• 期：3
• 页码：808-815
• 全文大小：489KB
• 刊物主题：Surgical Oncology; Oncology; Surgery;
• 出版者：Springer International Publishing
• ISSN：1534-4681
• 卷排序：24

文摘

BackgroundNeutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and lymphocyte-monocyte ratio (LMR) may serve as a simple index of the immune function. The aim of this study was to investigate the prognostic significance of NLR, PLR, and LMR in patients with resectable pancreatic ductal adenocarcinoma (PDAC) and to verify whether such biomarkers are associated with changes in populations of lymphoid cells.