Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis mice

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• 作者：Jinyu Li ; Yi Wei ; Xue Li ; Dashuai Zhu ; Bo Nie…
• 关键词：Xian ; fang ; huo ; ming ; Yin (XFHM) ; Lymphocyte ; Pro ; inflammatory cytokine ; Nuclear factor κB (NF ; κB) ; Janus ; activated kinase ; signal transducer and activator of transcription (JAK/STAT) ; Collagen ; induced arthritis (CIA)
• 刊名：BMC Complementary and Alternative Medicine
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：4650KB
• 刊物主题：Complementary & Alternative Medicine; Internal Medicine; Chiropractic Medicine;
• 出版者：BioMed Central
• ISSN：1472-6882
• 卷排序：17

文摘

BackgroundXian-Fang-Huo-Ming-Yin (XFHM), a traditional herbal formula, has been used to treat sores and carbuncles for hundreds of years in Asia. Nowadays, its clinical effects in treatment of rheumatoid arthritis (RA) have been validated. In this study, we want to study its possible molecular mechanisms of regulating the differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis (CIA) mice for RA treatment.