A quantitative transcriptomic analysis of the physiological significance of mTOR signaling in goat fetal fibroblasts

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• 作者：Yuting Fu ; Xu Zheng ; Xiaoyang Jia ; Uyanga Binderiya ; Yanfeng Wang&#8230
• 关键词：Goat ; RNA ; Seq ; Differential expression genes ; mTOR
• 刊名：BMC Genomics
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：17
• 期：1
• 全文大小：1899KB
• 刊物主题：Life Sciences, general; Microarrays; Proteomics; Animal Genetics and Genomics; Microbial Genetics and Genomics; Plant Genetics & Genomics;
• 出版者：BioMed Central
• ISSN：1471-2164
• 卷排序：17

文摘

BackgroundMammalian target of rapamycin (mTOR) is an evolutionarily conserved serine/threonine kinase that is a central regulator of cell growth and metabolism. CCI-779 is a specific inhibitor of the mTORC1 signaling pathway.