Bifidobacterium adolescentis protects against necrotizing enterocolitis and upregulates TOLLIP and SIGIRR in premature neonatal rats

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• 作者：Wenshen Wu ; Yanli Wang ; Jingjing Zou ; Fang Long ; Huiheng Yan ; Lijuan Zeng…
• 关键词：Necrotizing enterocolitis ; Toll ; like receptor 4 ; Toll interacting protein ; single Ig IL ; 1 ; Related receptor
• 刊名：BMC Pediatrics
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：17
• 期：1
• 全文大小：821KB
• 刊物主题：Pediatrics; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2431
• 卷排序：17

文摘

BackgroundNecrotizing enterocolitis (NEC) is a serious gastrointestinal disorder that is often seen in premature infants. Probiotics decrease the risk of NEC; however, the mechanism by which probiotics work is not clear. The goal of this study was to evaluate the preventive effect of Bifidobacterium adolescentis in an NEC rat model.