Is Needle Biopsy Clinically Useful in Preoperative Grading of Central Chondrosarcoma of the Pelvis and Long Bones?

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• 作者：Pablo D. Roitman MD ; Germán L. Farfalli MD…
• 刊名：Clinical Orthopaedics and Related Research®
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：475
• 期：3
• 页码：808-814
• 全文大小：764KB
• 刊物主题：Orthopedics; Surgical Orthopedics; Medicine/Public Health, general; Surgery; Sports Medicine; Conservative Orthopedics;
• 出版者：Springer US
• ISSN：1528-1132
• 卷排序：475

文摘

BackgroundCentral chondrosarcoma of bone is graded on a scale of 1 to 3 according to histological criteria. Clinically, these tumors can be divided into low-grade (Grade 1) and high-grade (Grade 2, Grade 3, and dedifferentiated) chondrosarcomas. Although en bloc resection has been the most widely used treatment, it has become generally accepted that in selected patients with low-grade chondrosarcomas of long bones, curettage is safe and effective. This approach requires an accurate preoperative estimation of grade to avoid under- or overtreatment, but prior reports have indicated that both imaging and biopsy do not always give an accurate prediction of grade.