Influence of New Modified Biliopancreatic Diversion on Blood Glucose and Lipids in GK rats

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• 作者：Shangeng Weng ; Bin Zhang ; Changguo Xu ; Su Feng ; Hongxing He
• 关键词：Plasma glucose ; Plasma lipid ; Goto ; Kakizaki rat ; Duodenal ; jejunal bypass ; Biliopancreatic juice
• 刊名：Obesity Surgery
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：27
• 期：3
• 页码：657-664
• 全文大小：
• 刊物主题：Surgery;
• 出版者：Springer US
• ISSN：1708-0428
• 卷排序：27

文摘

BackgroundThis study aimed to investigate the influence of new biliopancreatic diversion (NBPD) and duodenal-jejunal bypass (DJB) surgery on blood glucose, lipids, gastrointestinal hormones, and insulin in Goto-Kakizaki (GK) rats, an animal model for type 2 diabetes, in order to elucidate the mechanisms underlying the therapeutic effect of these types of surgery on this clinical condition.