Intraoperative radiation therapy for colon and rectal cancers: a clinical review

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• 作者：Michael G. Haddock
• 关键词：Colon cancer ; Rectal cancer ; IORT
• 刊名：Radiation Oncology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：12
• 期：1
• 全文大小：402KB
• 刊物主题：Cancer Research; Oncology; Radiotherapy; Imaging / Radiology;
• 出版者：BioMed Central
• ISSN：1748-717X
• 卷排序：12

文摘

Although there have been significant advances in the adjuvant therapy of colorectal cancer, results for patients have historically been poor when complete resection is unlikely or not possible. Similarly, locally recurrent colorectal cancer patients often experience significant tumor related morbidity and disease control and long term survival have historically been poor with standard therapies. Intraoperative radiation therapy (IORT) has been proposed as a possible tool for dose escalation in patients with locally advanced colorectal cancer.