Enhanced antibacterial effect of polypyrazole-graphene oxide composite

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• 作者：Bin Yang ; Yufei Wang ; Longqiang Xiao ; Xiaowen Hu ; Guofu Zhou
• 关键词：graphene oxide ; polypyrazole ; antibacterial nanohybrid ; hydrophobic ; dicyclohexylcarbodiimide (DCC) coupling
• 刊名：Macromolecular Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：25
• 期：1
• 页码：21-26
• 全文大小：
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Polymer Sciences; Soft and Granular Matter, Complex Fluids and Microfluidics; Physical Chemistry; Characterization and Evaluation of Materials; Nanochemistry; Nanotechnology;
• 出版者：The Polymer Society of Korea
• ISSN：2092-7673
• 卷排序：25

文摘

Besides excellent physical performances, graphene oxide (GO) has been widely acknowledged as a potential antibacterial material. Chemical modification of GO was taken out with polypyrazole by facile amidation in the presence of dicyclohexylcarbodiimide (DCC) and then generated polypyrazole-graphene oxide (FGO) nanohybrid. FGO nanohybrid showed smooth and multilayer structures by scanning electron microscopy. The value of static water contact angle of FGO is 103°, suggesting FGO was a hydrophobic material. Thermo gravimetric analysis of FGO showed a 65% mass loss up 50 to 600 °C, suggesting that FGO is a thermal stability material. Inactivation efficiency test of nominal Escherichia coli cells showed that the viability greatly decreased to 7% after 4 h incubation with FGO under 37 °C, indicating an outstanding antibacterial ability of FGO much better than that of polypyrazole and GO.