Efficacy of a novel formulation of L-Carnitine, creatine, and leucine on lean body mass and functional muscle strength in healthy older adults: a randomized, double-blind placebo-controlled study

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• 作者：Malkanthi Evans ; Najla Guthrie ; John Pezzullo ; Toran Sanli…
• 关键词：Sarcopenia ; L ; Carnitine ; L ; leucine ; Creatine ; Aging ; Muscle strength ; Lean body mass ; Older adults ; mTOR
• 刊名：Nutrition & Metabolism
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：14
• 期：1
• 全文大小：923KB
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Clinical Nutrition; Metabolic Diseases;
• 出版者：BioMed Central
• ISSN：1743-7075
• 卷排序：14

文摘

BackgroundProgressive decline in skeletal muscle mass and function are growing concerns in an aging population. Diet and physical activity are important for muscle maintenance but these requirements are not always met. This highlights the potential for nutritional supplementation. As a primary objective, we sought to assess the effect of a novel combination of L-Carnitine, creatine and leucine on muscle mass and performance in older subjects.