Double stimuli responsive mixed aggregates from poly(acrylic acid)-block-poly(ε-caprolactone)-block-poly(acrylic acid) and poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) triblock copolymers

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• 作者：Katya Kamenova ; Barbara Trzebicka ; Denitsa Momekova ; Petar Petrov
• 关键词：Amphiphilic copolymers ; Double stimuli responsive aggregates ; ATRP
• 刊名：Polymer Bulletin
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：74
• 期：3
• 页码：707-720
• 全文大小：
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Polymer Sciences; Soft and Granular Matter, Complex Fluids and Microfluidics; Characterization and Evaluation of Materials; Physical Chemistry;
• 出版者：Springer Berlin Heidelberg
• ISSN：1436-2449
• 卷排序：74

文摘

Well defined ABA triblock copolymer comprising a biodegradable poly(ε-caprolactone) (PCL) middle block and two pH responsive poly(acrylic acid) (PAA) outer blocks was synthesized by atom transfer radical polymerization of tert-butyl acrylate, initiated by PCL-based macroinitiator, followed by selective hydrolysis of the poly(tert-butyl acrylate) blocks. The cooperative self-assembly of the synthesized poly(acrylic acid)-block-poly(ε-caprolactone)-block-poly(acrylic acid) (PAA₂₂PCL₂₆PAA₂₂) copolymer with a temperature-responsive poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide) (PEO₂₆PPO₄₀PEO₂₆, Pluronic P85) triblock copolymer at different compositions in aqueous media was investigated. Based on experimental data, copolymer properties and composition, formation of nano-sized aggregates comprising a mixed PCL/PPO core and a mixed PEO/PAA corona is suggested. The binary mixture of PAA₂₂PCL₂₆PAA₂₂:PEO₂₆PPO₄₀PEO₂₆ copolymers at molar ratio 3:1 favors the formation of mixed aggregates only, while at higher PEO₂₆PPO₄₀PEO₂₆ content the aggregates coexist with pure PEO₂₆PPO₄₀PEO₂₆ micelles.