Fluid and structure coupling analysis of the interaction between aqueous humor and iris

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• 作者：Wenjia Wang ; Xiuqing Qian ; Hongfang Song ; Mindi Zhang&#8230
• 关键词：Aqueous humor ; Iris deformation ; Intraocular pressure ; Mechanical properties ; Fluid–structure interaction
• 刊名：BioMedical Engineering OnLine
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：15
• 期：2-supp
• 全文大小：2381KB
• 刊物类别：Engineering
• 刊物主题：Biomedical Engineering; Biomaterials; Biotechnology; Biomedical Engineering/Biotechnology;
• 出版者：BioMed Central
• ISSN：1475-925X
• 卷排序：15

文摘

BackgroundGlaucoma is the primary cause of irreversible blindness worldwide associated with high intraocular pressure (IOP). Elevated intraocular pressure will affect the normal aqueous humor outflow, resulting in deformation of iris. However, the deformation ability of iris is closely related to its material properties. Meanwhile, the passive deformation of the iris aggravates the pupillary block and angle closure. The nature of the interaction mechanism of iris deformation and aqueous humor fluid flow has not been fully understood and has been somewhat a controversial issue. The purpose here was to study the effect of IOP, localization, and temperature on the flow of the aqueous humor and the deformation of iris interacted by aqueous humor fluid flow.