Transarterial embolization combined with RNA interference targeting hypoxia-inducible factor-1α for hepatocellular carcinoma: a preliminary study of rat model

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• 作者：Jia-yan Ni ; Lin-feng Xu ; Wei-dong Wang…
• 关键词：Hypoxia ; inducible factor ; 1α ; Vascular endothelial growth factor ; RNA interference ; Transarterial embolization ; Hepatocellular carcinoma
• 刊名：Journal of Cancer Research and Clinical Oncology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：143
• 期：2
• 页码：199-207
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Oncology; Cancer Research; Internal Medicine; Hematology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-1335
• 卷排序：143

文摘

PurposeTo study whether transarterial embolization (TAE) with RNA interference (RNAi) targeting hypoxia-inducible factor-1α (HIF-1α) can improve efficacy of TAE in treating hepatocellular carcinoma (HCC).