Konfokale Mikroskopie als früher Rezidivmarker nach Keratoplastik infolge einer Fusarium-solani-Keratitis

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• 作者：L. Daas ; M. Bischoff-Jung ; A. Viestenz ; B. Seitz ; A. Viestenz
• 关键词：SchlüsselwörterMykotische Keratitis ; Konfokale Mikroskopie ; Hyperreflektive Linien ; Rezidivmarker ; Fusarium solani
• 刊名：Der Ophthalmologe
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：114
• 期：1
• 页码：66-69
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Ophthalmology;
• 出版者：Springer Medizin
• ISSN：1433-0423
• 卷排序：114

文摘

In the case of therapy-resistant keratitis an infection with Fusarium solani should be taken into consideration as a rare but very severe eye disease. In the majority of cases Fusarium solani keratitis will result in a protracted clinical course despite aggressive medicinal and surgical interventions. We describe the case of a referred patient after intensive topical, intracameral and systemic antibacterial and antimycotic therapy as well as surgical treatment with emergency keratoplasty à chaud because of Fusarium solani keratitis. The patient presented to our department with persistent discomfort for further therapeutic interventions. Using confocal microscopy we were able to demonstrate the presence of fungal hyphae in the host cornea and the graft, which was important for making further surgical decisions. Furthermore, this emphasizes the role of confocal microscopy as an early relapse marker during the clinical monitoring.