Autoimmune arthritis deteriorates bone quantity and quality of periarticular bone in a mouse model of rheumatoid arthritis

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• 作者：T. Shimizu ; M. Takahata ; H. Kimura-Suda ; Y. Kameda ; K. Endo…
• 关键词：Bone fragility ; Bone quality ; Cortical bone ; Rheumatoid arthritis (RA)
• 刊名：Osteoporosis International
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：28
• 期：2
• 页码：709-718
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Orthopedics; Endocrinology; Rheumatology;
• 出版者：Springer London
• ISSN：1433-2965
• 卷排序：28

文摘

SummaryThis study showed that autoimmune arthritis induces especially severe osteoporosis in the periarticular region adjacent to inflamed joints, suggesting that arthritis increases the fragility fracture risk near inflamed joints, which is frequently observed in patients with RA.