Long noncoding RNA GAS5 inhibits malignant proliferation and chemotherapy resistance to doxorubicin in bladder transitional cell carcinoma

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• 作者：Hui Zhang ; Yan Guo ; Yongsheng Song ; Chao Shang
• 关键词：Long noncoding RNA ; GAS5 ; Bladder transitional cell carcinoma ; Chemotherapy ; Doxorubicin
• 刊名：Cancer Chemotherapy and Pharmacology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：79
• 期：1
• 页码：49-55
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Oncology; Pharmacology/Toxicology; Cancer Research;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-0843
• 卷排序：79

文摘

PurposeBladder cancer is the most general malignant cancer in genitourinary system, more than 90% of BCs are bladder transitional cell carcinomas (BTCC). This study aimed to investigate the clinical significance of growth arrest-specific 5 (GAS5) gene and its regulatory effects of malignant proliferation and chemotherapy resistance to doxorubicin in BTCC cells.