First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children’s Oncology Group Phase 1/Pilot Consortium

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• 作者：Frank M. Balis ; Patrick A. Thompson ; Yael P. Mosse…
• 关键词：Crizotinib ; Pharmacokinetics ; Childhood cancer ; Children ; ALK
• 刊名：Cancer Chemotherapy and Pharmacology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：79
• 期：1
• 页码：181-187
• 全文大小：1332KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Oncology; Pharmacology/Toxicology; Cancer Research;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-0843
• 卷排序：79

文摘

PurposeCharacterize the pharmacokinetics of oral crizotinib in children with cancer.