Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein

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• 作者：Yulei Chen ; Siyuan Zhang ; Qizhi Wang ; Xiaobo Zhang
• 关键词：AP ; 1 ; Cancer metastasis ; CHI3L1 ; IL ; 13Rα2 ; M2 macrophage
• 刊名：Journal of Hematology & Oncology
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：10
• 期：1
• 全文大小：8060KB
• 刊物主题：Oncology; Hematology; Cancer Research;
• 出版者：BioMed Central
• ISSN：1756-8722
• 卷排序：10

文摘

BackgroundThe macrophage, one of the several key immune cell types, is believed to be involved in tumorigenesis. However, the mechanism of macrophages promoting tumor progression is largely unknown.