Metabolic heterogeneity of the normal human brain: multivariate analysis of ¹H MRS in vivo spectra acquired at 3T

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• 作者：Agnieszka Skorupa ; Łukasz Boguszewicz ; Marek Kijonka ; Maria Sokół
• 关键词：Normal brain ; Multivariate analysis ; 1H MRS in vivo ; Metabolism
• 刊名：Metabolomics
• 出版年：2017
• 出版时间：April 2017
• 年：2017
• 卷：13
• 期：4
• 全文大小：
• 刊物主题：Biochemistry, general; Molecular Medicine; Cell Biology; Developmental Biology; Biomedicine, general;
• 出版者：Springer US
• ISSN：1573-3890
• 卷排序：13

文摘

IntroductionIn recent years multivariate projection techniques of data analysis (PCA, PLS-DA) have been increasingly used for detection of complex 1H MRS derived metabolic signatures in pathologic conditions. However, these techniques have not been applied in the studies of metabolic heterogeneity of the normal human brain.