The lncRNA CRNDE promotes colorectal cancer cell proliferation and chemoresistance via miR-181a-5p-mediated regulation of Wnt/β-catenin signaling

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• 作者：Peng Han ; Jing-wen Li ; Bo-miao Zhang ; Jia-chen Lv ; Yong-min Li…
• 关键词：CRNDE ; miR ; 181a ; 5p ; Wnt/β ; catenin signaling ; Colorectal cancer ; Proliferation ; Chemoresistance
• 刊名：Molecular Cancer
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：16
• 期：1
• 全文大小：3882KB
• 刊物主题：Cancer Research; Oncology;
• 出版者：BioMed Central
• ISSN：1476-4598
• 卷排序：16

文摘

BackgroundWith more than 600,000 mortalities each year, colorectal cancer (CRC) is the third most commonly diagnosed type of cancer worldwide. Recently, mechanisms involving noncoding RNAs have been implicated in the development of CRC.