The technology which is being developed based on the seismic entropy method for monitoring and forecasting the earthquakes in the territory of Russia is described. This technology relies on seismostatistics and makes it possible to automate the monitoring system and to efficiently tap the networks of ground-based and ground-and-satellite-based observations of operative precursors. The main seismic systems responsible for the preparation of the strong earthquakes with magnitudes М ≥ 5.5 are described. The track and energy diagrams constructed for each seismic system provide the means for monitoring the preparation and forecasting the strong earthquakes in the real-time mode. Forty-four seismic systems controlling almost all seismically hazardous regions in Russia were identified and tested in real time during the period from 2010 to 2015. The guidelines for the practical application of the results of monitoring and forecasting are developed.