Modelling Stem Cells Lineages with Markov Trees

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• 作者：Victor Olariu ; Daniel Coca ; Stephen A. Billings ; Visakan Kadirkamanathan
• 刊名：Lecture Notes in Computer Science
• 出版年：2009
• 出版时间：2009
• 年：2009
• 卷：5780
• 期：1
• 页码：233-243
• 全文大小：228.9 KB

文摘

A variational Bayesian EM with smoothed probabilities algorithm for hidden Markov trees (HMT) is proposed for incomplete tree structured data. The full posterior of the HMT parameters is determined and the underflow problems associated with previous algorithms are eliminated. Example results for the prediction of the types of cells in real stem cell lineage trees are presented.