FRD上皮组织特殊染色液筛查宫颈病变的应用研究

英文论文题名：Application of FRD epithelial tissue special staining solution in screening of cervical lesions
论文作者：李开颜 ; 蔡海莹 ; 沈慧敏
英文论文作者：Li Kaiyan ; Cai Haiying ; Shen Huimin ; Department of Obstetrics and Gynecology ; Chaozhou Chao'an District People's Hospital ; Department of Obstetrics and Gynecology ; The First Affiliated Hospital of Sun Yat-Sen University
年：2016
作者机构：广东省潮州市潮安区人民医院妇产科;中山大学附属第一医院妇产科;
论文关键词：FRD上皮组织特殊染色 ; TCT ; HPV DNA ; 筛查 ; 宫颈病变
英文论文关键词：FRD epithelial tissue special staining ; HPV ; DNA TCT ; screening ; cervical lesions
会议召开时间：2016-05-13
会议录名称：中国毒理学会中药与天然药物毒理专业委员会第一次（2016年）学术交流大会论文集
语种：中文
分类号：R711
学会代码：ZGDV
会议名称：中国毒理学会中药与天然药物毒理专业委员会第一次（2016年）学术交流大会
会议地点：中国天津
主办单位：中国毒理学会中药与天然药物毒理专业委员会
学会名称：中国毒理学会
页数：6
文件大小：495k
原文格式：O
会议级别：全国

摘要

目的:研究FRD上皮组织特殊染色液筛查宫颈病变的应用。方法:选取2014年1月到2015年8月于我院和中山大学附属第一医院就诊的妇科患者,FRD染色检查宫颈病变,共500例为研究对象。所有患者进行FRD染色,同时进行TCT及HPV DNA检测。三者任意一项异常则进一步行阴道镜检查,若患者宫颈外口异常,则根据阴道镜结果于该处组织活检。结果:本组500例患者中,FRD检测结果阳性324例,阴性176例;阴道镜检测结果表明,阳性宫颈炎症111例,CINⅠ159例,CINⅡ45例,CINⅢ9例;FRD与阴道镜病理检测结果符合率为78.34%。TCT检测结果NILM 184例,ASCUS170例,ASCUS—H 77例,LSIL50例,HSIL19例;TCT检测与阴道镜病理检测结果符合率为54.89%。HPV检测结果阳性258例,阴性242例;阴道镜检测结果表明,阳性宫颈炎症111例,CINⅠ159例,CINⅡ45例,CINⅢ9例;FRD与阴道镜病理检测结果符合率为62.30%。病变诊断中,HPVObjective:To investigate the application of FRD epithelial tissue special staining solution in screening of cervical lesions.Methods:500 cases of patients were selected.FRD staining was performed in all patients,and HPV and DNA TCT were detected simultaneously.Any abnormality of the three will be further checked,if the patients with abnormal cervical mouth,according to the results of the vaginal biopsy.Results:500 cases of this group of patients,FRD positive test results of 324 cases,176 cases were negative;colposcopy examination results show that,111 patients with positive cervical inflammation,159 patients of CIN I,45 cases of CIN II,9 cases of cervical intraepithelial neoplasia;FRD and colposcopy pathological examination results accord with the rate was 78.34%.Rate.TCT nilm 184 cases,170 cases of ASCUS,ASCUSH 77 cases,LSIL50,19 cases with HSIL;thinprep cytologic test and colposcopy pathological examination results with rate of 54.89%.HPV test results were positive in 258 cases,negative in 242 cases.The results showed that the test results showed that 111 cases of positive cervicitis,CIN Ⅰ 159 cases,CIN Ⅱ in 45 cases,CTN Ⅲ in 9 cases;FRD and pathological examination results in accordance with the rate of62.30%.HPV

引文

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