摘要
研究目的:观察偏瘫康复丸治疗缺血性脑卒中后下肢深静脉血栓形成的临床疗效、作用机理以及对D一二聚体、血脂、血液流变学的影响。
方法:研究对象从我院2007年6月至2009年2月期间神经科住院的脑卒中患者中筛选,64例缺血性脑卒中患者分为偏瘫康复丸试验组32例,对照组32例。对照组给予常规西药治疗,试验组在常规西药治疗基础上加用偏瘫康复丸。观察两组治疗前后症状、体征、彩色血管超声、D一二聚体、血脂、血液流变学的变化,并记录在案,随时观察不良反应情况。痊愈病例在停止治疗后1-2个月进行随访。
结果:试验组总有效率100.00%,对照组总有效率93.75%,两组差异有显著性意义。在改善病人临床症状方面,试验组优于对照组(P＜0.05),在改善D一二聚体、血脂、血液流变学的变化作用方面亦优于对照组(P＜0.05)。
结论:偏瘫康复丸对治疗缺血性脑卒中后下肢深静脉血栓形成有较好的疗效,能消溶血栓,建立侧支循环,并可降低血脂、血液粘度,明显减轻水肿胀痛,而且临床无不良反应,安全、可靠。
Objective: To observe the clinical effect of PianTanKangFu Pill on Treating Deep Venous Thrombosis after Ischemia Stroke and its action on blood stream rheology , D-dimer, blood rheology and coagulation, explore its mechanism.
Methods: The study from our hospital from June 2007 to February 2009 during the neurological stroke patients hospitalized in the screening, 64 cases of acute ischemic stroke patients were divided into experimental group PianTanKangFu pill 32 cases, 32 cases of the control group. Control group given conventional western medicine treatment, the experimental group treated with conventional Western medicine with PianTanKangFu add up pills. The two groups were observed before and after treatment symptoms, signs, color vascular ultrasound, D-dimer, blood rheology changes and for the record, at any time to observe the situation of adverse reactions. Cases cured after treatment cessation at 1-2 months follow-up.
Results: Experimental group total effectiveness 100.00%, control group total effectiveness 93.75%, two groups of differences have the significance.In improving the patient clinical symptom aspect, the experimental group surpasses the control group (P<0.05), is improving D-dimer, the blood fats, the blood rheology change function aspect also surpasses the control group (P<0.05).
Conclusion: PianTanKangFu pill on Treating Acute Deep Venous Thrombosis after Ischemia Stroke has better curative effect, can eliminate thrombolytic, the establishment of collateral circulation, and reduces blood viscosity, significantly reduce the edema pain , but no adverse clinical response, safety and reliable.
引文
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