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Elsevier电子期刊(105)

在“Elsevier电子期刊”中，命中：105条，耗时：小于0.01 秒

在所有数据库中总计命中：105条

1.Identification of allosteric binding sites for PI3Kα oncogenic mutant specific inhibitor design

作者：Michelle S. Miller^a ; Sweta Maheshwari^b ; Fiona M. McRobb^c ; Kenneth W. Kinzler^d ; L. Mario Amzel^b ; Bert Vogelstein^d ; Sandra B. Gabelli^a ; ^b ; ^e ; ^{gabelli@jhmi.edu}

关键词：PIK3CA ; PI3K ; PIP2 ; PIP3 ; Fragment-based drug discovery

刊名：Bioorganic & Medicinal Chemistry

出版年：2017

2.Phosphoinositide 3-kinase γ ties chemoattractant- and adrenergic control of microglial motility

作者：Nadine Schneble^a ; ^{Nadine.Schneble@med.uni-jena.de} ; Caroline Schmidt^a ; ^{Caroline.Schmidt@med.uni-jena.de} ; Reinhard Bauer^a ; ^{Reinhard.Bauer@med.uni-jena.de} ; Jö ; rg P. Mü ; ller^a ; ^{Joerg.Mueller2@med.uni-jena.de} ; Shamci Monajembashi^b ; ^{shamci@fli-leibniz.de} ; Reinhard Wetzker^a ; ^{Reinhard.Wetzker@uni-jena.de}

关键词：Akt ; protein kinase Akt/PKB ; ATP ; Adenosine triphosphate ; C5a ; complement system component 5a ; C5aR ; complement system component 5a receptor ; cAMP ; Cyclic adenosine monophosphate ; DAPI ; 4&prime ; 6-diamidino-2-phenylindole ; HRP ; horseradish peroxidase ; PIP3 ; phosphatidylinositol (34 ; 5)-trisphosphate ; shRNA ; small hairpin RNA

刊名：Molecular and Cellular Neuroscience

出版年：2017

3.MiR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway

作者：Hongyu Shen^a ; ^b ; Dandan Wang^b ; Liangpeng Li^c ; Sujin Yang^a ; ^b ; Xiu Chen^a ; ^b ; Siying Zhou^b ; ^d ; Shanliang Zhong^e ; Jianhua Zhao^e ; ^{lcjyjhzhao@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jinhai Tang^a ; ^b ; ^{njmujhtang@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ADR ; adriamycin ; miRNA ; microRNA ; UTR ; untranslated region ; PTEN ; phosphatase a tensin homolog deleted on chromosome 10 ; PIP3 ; phosphatidylinositol-34 ; 5-triphosphate ; PIP2 ; diphosphate product ; IC50 ; the inhibitory concentration to produce 50% cell death ; FBS ; fetal bovine serum ; NC ; negative control ; PBS ; phosphate-buffered saline ; RT-qPCR ; real-time quantitative polymerase chain reaction assay ; MTT ; 3-[4 ; 5-dimethylthiazol-2-yl]-2 ; 5-diphenyltetrazolium-bromide ; DMSO ; dimethylsulfoxide ; KEGG ; K

刊名：Gene

出版年：2017

4.PI(3,4,5)P₃ Engagement Restricts Akt Activity to Cellular Membranes

作者：Michael Ebner¹ ; ³ ; Iva Lučić¹ ; ³ ; Thomas A. Leonard¹ ; ² ; ^{thomas.leonard@mfpl.ac.at} ; Ivan Yudushkin¹ ; ² ; ⁴ ; ^{ivan.yudushkin@mfpl.ac.at}

关键词：protein kinase B/Akt ; AGC kinases ; allostery ; cellular signaling ; signal transduction ; fluorescence correlation spectroscopy ; fluorescence cross-correlation spectroscopy ; cellular membranes ; phosphatidylinositol-34 ; 5-trisphosphate ; protein phosphatases

刊名：Molecular Cell

出版年：2017

5.SodC modulates ras and PKB signaling in Dictyostelium

作者：Boris Castillo^a ; Seon-Hee Kim^a ; Mujataba Sharief^b ; Tong Sun^a ; Lou W. Kim^b ; ^kiml@fiu.edu

关键词：Ras ; PKB ; Superoxide

刊名：European Journal of Cell Biology

出版年：2017

6.Class I phosphatidylinositol 3-kinase inhibitors for cancer therapy

作者：Wennan Zhao^&dagger ; ; Yuling Qiu^&dagger ; ; Dexin Kong ; ^{kongdexin@tmu.edu.cn}

关键词：Phosphatidylinositol 3-kinase ; PI3K inhibitor ; Drug candidate ; Cancer therapy ; PI3K/mTOR selectivity ; Anticancer

刊名：Acta Pharmaceutica Sinica B

出版年：2017

7.The F-actin modulator SWAP-70 controls podosome patterning in osteoclasts

作者：Anne Roscher^a ; Tomoka Hasegawa^b ; Sebastian Dohnke^c ; Carlos Ocañ ; a-Morgner^a ; Norio Amizuka^b ; Rolf Jessberger^a ; ¹ ; ^{rolf.jessberger@tu-dresden.de} ; Annette I. Garbe^a ; ^c ; ¹ ; ^{Annette.garbe@crt-dresden.de}

关键词：Actin cytoskeleton ; Podosome pattering ; Membrane binding ; PIP3 ; Swap-70 ; V-ATPase

刊名：Bone Reports

出版年：2016

8.Lipid regulators of Pkh2 in Candida albicans, the protein kinase ortholog of mammalian PDK1

作者：Daniel Pastor-Flores^a ; Jö ; rg O. Schulze^a ; Anna Bahí ; ^b ; ^c ; Evelyn Sü ; ß ; ^a ; Antonio Casamayor^b ; ^c ; ^{antonio.casamayor@uab.es" class="auth_mail" title="E-mail the corresponding author} ; Ricardo M. Biondi^a ; ^{biondi@med.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Budding yeast ; C. albicans ; Pkh ; PDK1 ; Cell wall integrity ; Allostery ; Sphingosine ; PHS ; DHS ; PI(3 ; 4)P2 ; PI(4 ; 5)P2 ; PI(34 ; 5)P3 ; PIP3 ; Sulfatide ; Phosphatidic acid ; Phosphatidylserine ; Phosphatidylethanolamine ; Phosphatidylcholine

刊名：Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids

出版年：2016

9.Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells

作者：Karen E. Anderson^a ; ^{karen.anderson@babraham.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Veronique Juvin^a ; ^{veronique.juvin@babraham.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Jonathan Clark^b ; ^{jonathan.clark@babraham.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Len R. Stephens^a ; ¹ ; ^{len.stephens@babraham.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Phillip T. Hawkins^a ; ¹ ; ^{phillip.hawkins@babraham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Arachidonate ; Phosphoinositides ; MCF10a cells ; PIP3

刊名：Advances in Biological Regulation

出版年：2016

10.Abrogated cardio protective effect of ischemic preconditioning in hyperhomocysteinemia and hypertrophy

作者：Shaiba Sana Qureshi ; Ahsas Goyal ; ^{ahsasgoyal1990@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：(I&ndash ; R) ; ischemia&ndash ; reperfusion injury ; IPC ; ischemia preconditioning ; ROS ; reactive oxygen species ; RNS ; reactive nitrogen species ; (ONOO&minus) ; peroxynitrite ; PI3K ; phosphatidylinositol 3-kinase ; PIP3 ; phosphatidyl-inositol 34 ; 5-triphosphate ; PIP2 ; phosphatidyl inositol 3 ; 4-biphosphate ; PDK1 ; phosphoinositide-dependent kinase ; mitoKATP ; mitochondrial ATP-sensitive potassium channels ; DAG ; diacylglycerol ; IP3 ; inositol triphosphate ; PKC ; protein kinase C ; mPTP ; mitochondrial permeabi

刊名：Journal of Indian College of Cardiology

出版年：2016

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