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Elsevier电子期刊(17)

在“Elsevier电子期刊”中，命中：17条，耗时：0.0899869 秒

在所有数据库中总计命中：49条

1.Efficacy, safety, and pharmacokinetics of natalizumab in Japanese multiple sclerosis patients: A double-blind, randomized controlled trial and open-label pharmacokinetic study

作者：Takahiko Saida^a ; ^{saida_takahiko@maia.eonet.ne.jp} ; Jun-ichi Kira^b ; Shuji Kishida^c ; Takashi Yamamura^d ; Yukiko Sudo^e ; Kazutaka Ogiwara^e ; JT Tibung^e ; Nisha Lucas^f ; Meena Subramanyam^f ; On behalf of Natalizumab Trial Principal Investigators

关键词：AE ; adverse event ; ARR ; annualized relapse rate ; AUC ; area under the concentration time curve ; AUC0&ndash ; last ; area under the curve to the last measurable concentration of a dosing interval ; AUC0&ndash ; &infin ; area under the curve to infinity ; AUC0&ndash ; 672 ; area under the curve for dosing interval ; CI ; confidence interval ; CL ; systemic clearance ; Cmax ; maximum concentration ; Ctrough ; trough concentration ; EDSS ; Expanded Disability Status Scale ; ELISA ; enzyme-linked immunosorbent assay ; Gd ; g

刊名：Multiple Sclerosis and Related Disorders

出版年：2017

2.Abuse liability assessment of eslicarbazepine acetate in healthy male and female recreational sedative users: A Phase I randomized controlled trial

作者：Naama Levy-Cooperman^a ; ¹ ; ^{nlevy-cooperman@altreos.com" class="auth_mail" title="E-mail the corresponding author} ; Kerri A. Schoedel^a ; ¹ ; ^{kschoedel@altreos.com" class="auth_mail" title="E-mail the corresponding author} ; Bijan Chakraborty^a ; ² ; ^{bijan.chakraborty@rogers.com" class="auth_mail" title="E-mail the corresponding author} ; David Blum^b ; ^{david.blum@sunovion.com" class="auth_mail" title="E-mail the corresponding author} ; Hailong Cheng^b ; ^{hailong.cheng@sunovion.com" class="auth_mail" title="E-mail the corresponding author}

关键词：λz ; elimination rate constant ; AED ; antiepileptic drug ; AE ; adverse event ; ANCOVA ; analysis of covariance ; ARCI ; Addiction Research Center Inventory ; ALP ; alprazolam ; AST ; aspartate aminotransferase ; AUC ; area under the curve ; AUC0&ndash ; last ; AUC from time zero to the last measurable concentration ; AUC0&ndash ; &infin ; ; AUC from time zero to infinity ; BMI ; body mass index ; CI ; confidence interval ; CL/F ; apparent total clearance ; Cmax ; maximum observed plasma concentration ; CNS ; central nerv

刊名：Epilepsy & Behavior

出版年：2016

3.Single-dose Pharmacokinetic Properties and Relative Bioavailability of a Novel Methylphenidate Extended-release Chewable Tablet Compared With Immediate-release Methylphenidate Chewable Tablet

作者：Richat Abbas ; PhD¹ ; ^{Richat.abbas-borhan@pfizer.com" class="auth_mail" title="E-mail the corresponding author} ; Donna Palumbo ; PhD¹ ; Faith Walters ; PharmD¹ ; Heidi Belden ; PharmD¹ ; Sally A. Berry ; MD ; PhD²

关键词：attention-deficit/hyperactivity disorder ; bioavailability ; dose forms ; methylphenidate ; pharmacokinetic properties

刊名：Clinical Therapeutics

出版年：2016

4.Evaluation of the toxicology and pharmacokinetics of recombinant factor VIII Fc fusion protein in animals

作者：Jennifer A. Dumont ; ^{jennifer.dumont@biogen.com" class="auth_mail" title="E-mail the corresponding author} ; Kenneth S. Loveday ^{kenneth.loveday@biogen.com" class="auth_mail" title="E-mail the corresponding author} ; David R. Light ^{david.light@biogen.com" class="auth_mail" title="E-mail the corresponding author} ; Glenn F. Pierce ^{glennfpierce@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Haiyan Jiang ^{haiyan.jiang@biogen.com" class="auth_mail" title="E-mail the corresponding author}

关键词：aPTT ; activated partial thromboplastin time ; AUC&infin ; area under the curve from zero to time infinity ; AUClast ; area under the curve up to the last measurable concentration ; BW ; body weight ; CL ; clearance ; Cmax ; maximum plasma concentration ; ECG ; electrocardiogram ; ELISA ; enzyme-linked immunosorbent assay ; F ; female ; FcRn ; neonatal Fc receptor ; FVIII ; factor VIII ; GLP ; Good Laboratory Practice ; HEK ; human embryonic kidney ; HR ; heart rate ; IgG1 ; immunoglobulin G1 ; M ; male ; MRT ; mean residence

刊名：Thrombosis Research

出版年：2015

5.Population pharmacokinetics of fluticasone propionate/salmeterol using two different dry powder inhalers

作者：K. Soulele^a ; P. Macheras^a ; L. Silvestro^b ; S. Rizea Savu^b ; V. Karalis^a ; ^{vkaralis@pharm.uoa.gr" class="auth_mail" title="E-mail the corresponding author}

关键词：90% CI ; 90% confidence interval ; ANOVA ; analysis of variance ; AUCinf ; area under the C&ndash ; t curve from time zero extrapolated to infinity (pg/mL/h) ; AUCt ; area under the concentration&ndash ; time curve from time zero to the last sampling point or the last measurable concentration ; whichever occurs earlier (pg/mL/h) ; BE ; bioequivalence ; BMI ; body mass index (kg/m2) ; BSV% ; between subject variability (in %) ; BW ; body weight (kg) ; C ; concentration (pg/mL) ; CL ; clearance of the drug (L/h) ; Clast

刊名：European Journal of Pharmaceutical Sciences

出版年：2015

6.Identifying the limits for ellagic acid bioavailability: A crossover pharmacokinetic study in healthy volunteers after consumption of pomegranate extracts

作者：Antonio Gonzá ; lez-Sarrí ; as^a ; ¹ ; Rocí ; o Garcí ; a-Villalba^a ; ¹ ; M. Á ; ngeles Nú ; ñ ; ez-Sá ; nchez^a ; Joao Tomé ; -Carneiro^a ; Pilar Zafrilla^b ; Juana Mulero^b ; Francisco A. Tomá ; s-Barberá ; n^a ; Juan Carlos Espí ; n^a ; ^{jcespin@cebas.csic.es" class="auth_mail" title="E-mail the corresponding author}

关键词：AUCall ; area under the plasma concentration-time curve from the time of dosing to the time of the last observation ; BMI ; body mass index ; Cmax ; maximum plasma concentration ; EA ; ellagic acid ; ET ; ellagitannin ; MRTlast ; mean residence time for a molecule to reside in the body calculated from the time of dosing to the time of the last measurable concentration ; PE-1 ; pomegranate extract with low punicalagin/EA ratio ; PE-2 ; pomegranate extrat with high punicalagin/EA ratio ; Uro-A ; urolithin A ; Uro-B

刊名：Journal of Functional Foods

出版年：2015

7.Enantioselective determination of ornidazole in human plasma by liquid chromatography-tandem mass spectrometry on a Chiral-AGP column

作者：Jiangbo Du ; Zhiyu Ma ; Yifan Zhang ; Ting Wang ; Xiaoyan Chen ; Dafang Zhong

关键词：APCI ; atmospheric pressure chemical ionization ; AUC0&ndasht ; area under the concentration&ndash ; time curve to the last measurable concentration ; AUC0&ndash ; &infin ; area under plasma concentration&ndash ; time curve to infinity ; CL/F ; total body clearance

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：2013

8.Pharmacokinetic Profile of Beclomethasone Dipropionate Hydrofluoroalkane After Intranasal Administration Versus Oral Inhalation in Healthy Subjects: Results of a Single-Dose, Randomized, Open-Label, 3-Period Crossover Study

作者：Paul H. Ratner ; MD¹ ; ^{pratner@sylvanaresearch.com} ; Amy Melchior ; MS² ; Stephanie A. Dunbar ; PhD² ; Sudeesh K. Tantry ; PhD² ; Paul M. Dorinsky ; MD²

关键词：17-BMP ; allergic rhinitis ; BDP ; beclomethasone dipropionate ; intranasal ; nasal aerosol ; pharmacokinetics ; systemic bioavailability

刊名：Clinical Therapeutics

出版年：2012

9.Pharmacokinetic behavior of 16-dehydropregnenolone after intramuscular administration in rats

作者：Hong-Ying Yang¹ ; Wen-Meng Zhang¹ ; Wen-Wen Yang¹ ; Ting Zhao² ; Li-Xin Sun¹ ; ^{sunlixin67@yahoo.com}

关键词：16-dehydropregnenolone ; intramuscular administration ; pharmacokinetics ; high Performance liquid chromatography

刊名：Journal of Pharmaceutical Analysis

出版年：2011

10.Latanoprost Systemic Exposure in Pediatric and Adult Patients with Glaucoma: A Phase 1, Open-Label Study

作者：Susan Raber PharmD¹ ; ; ^{susan.raber@pfizer.com} ; Rachel Courtney PhD¹ ; Tomoko Maeda-Chubachi MD ; PhD¹ ; Brad D. Simons MD ; PhD² ; Sharon F. Freedman MD³ ; Barbara Wirostko MD⁴ ; A6111139 Study Group

刊名：Ophthalmology

出版年：2011

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