作者：Laura de Diego-Garcí ; a^a ; ^c ; Mercedes Ramí ; rez-Escudero^a ; Á ; lvaro Sebastiá ; n-Serrano^a ; ^c ; Juan Ignacio Diaz-Herná ; ndez^a ; ^d ; Jesú ; s Pintor^b ; José ; J. Lucas^d ; ^e ; Miguel Dí ; az-Herná ; ndez^a ; ^c ; ^{migueldiaz@ucm.es}

关键词：UPS ; Ubiquitin-Proteasome System ; P2Y2R ; P2Y2 receptor ; IP3 ; inositol 14 ; 5-trisphosphate ; MEK1/2 ; MAP kinase kinases ; ERK ; extracellular signal-regulated kinase ; PKC ; protein kinase C ; PKA ; protein kinase A ; PI3K ; inositol 14 ; 5-trisphosphate 3-kinases ; MAPK/ERK ; mitogen-activated protein kinases ; GFP ; green fluorescent protein ; YFP ; yellow fluorescent protein ; ATP ; adenosine triphosphate ; UTP ; uridine triphosphate ; PPADS ; pyridoxalphosphate-6-azophenyl-2&prime ; 4&prime ; -disulfonic acid ; Up4U

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2017

作者：Michael Ebner¹ ; ³ ; Iva Lučić¹ ; ³ ; Thomas A. Leonard¹ ; ² ; ^{thomas.leonard@mfpl.ac.at} ; Ivan Yudushkin¹ ; ² ; ⁴ ; ^{ivan.yudushkin@mfpl.ac.at}

关键词：protein kinase B/Akt ; AGC kinases ; allostery ; cellular signaling ; signal transduction ; fluorescence correlation spectroscopy ; fluorescence cross-correlation spectroscopy ; cellular membranes ; phosphatidylinositol-34 ; 5-trisphosphate ; protein phosphatases

刊名：Molecular Cell

出版年：2017

作者：Wennan Zhao^&dagger ; ; Yuling Qiu^&dagger ; ; Dexin Kong ; ^{kongdexin@tmu.edu.cn}

关键词：Phosphatidylinositol 3-kinase ; PI3K inhibitor ; Drug candidate ; Cancer therapy ; PI3K/mTOR selectivity ; Anticancer

刊名：Acta Pharmaceutica Sinica B

出版年：2017

作者：Ariane Scoumanne^a ; ¹ ; Patricia Molina-Ortiz^a ; Daniel Monteyne^b ; David Perez-Morga^b ; ^c ; Christophe Erneux^d ; Sté ; phane Schurmans^a ; ^{sschurmans@ulg.ac.be" class="auth_mail" title="E-mail the corresponding author}

关键词：Inositol 134 ; 5-tetrakisphosphate ; Inositol 14 ; 5-trisphosphate 3-kinase ; Itpkc ; Tissue expression ; Mouse

刊名：Advances in Biological Regulation

出版年：2016

作者：Robert Roskoski Jr. ^{rrj@brimr.org" class="auth_mail" title="E-mail the corresponding author}

关键词：AS ; activation segment ; CLL ; chronic lymphocytic leukemia ; CS or C-spine ; catalytic spine ; CL ; catalytic loop ; HΦ or Φ ; hydrophobic ; IP3 ; inositol 14 ; 5 trisphosphate ; IP6 ; inositol 12345 ; 6 hexakisphosphate ; MCL ; mantle cell lymphoma ; MW ; molecular weight ; NSCLC ; non-small cell lung cancer ; PKA ; protein kinase A ; PIP2 ; phosphatidyl inositol 4 ; 5 bisphosphate ; PIP3 ; phosphatidyl inositol 34 ; 5 trisphosphate ; RA ; rheumatoid arthritis ; RS or R-spine ; regulatory spine ; Sh1 ; shell residue 1 ; WM ; W

刊名：Pharmacological Research

出版年：2016

作者：Jing Gao^a ; Makiko Hirata^a ; ^b ; Akiko Mizokami^a ; Jin Zhao^a ; Ichiro Takahashi^b ; Hiroshi Takeuchi^c ; Masato Hirata^a ; ^{hirata1@dent.kyushu-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：CSP ; cysteine string protein ; FSK ; forskolin ; GST ; glutathione S-transferase ; Ins(14 ; 5)P3 ; d-myo-inositol 14 ; 5-trisphosphate ; KO ; knock out ; NA ; noradrenalin ; NSF ; N-ethylmaleimide-sensitive factor ; PKA ; cAMP-dependent protein kinase ; PKC ; protein kinase C ; PMA ; phorbol 12-myristate 13-acetate ; SDS ; sodium dodecyl sulfate ; SNAP-25 ; synaptosomal-associated protein of 25  ; kDa ; SNARE ; soluble NSF-attachment protein receptors ; VAMP ; vesicle-associated membrane protein ; WT ; wild type

刊名：Cellular Signalling

出版年：2016

作者：A. Tabernero ; ^{ataber@usal.es" class="auth_mail" title="E-mail the corresponding author} ; E. Gangoso^&dagger ; ; M. Jaraí ; z-Rodrí ; guez ; J.M. Medina

关键词：Cx43 ; connexin43 ; Cx43CT ; C-terminal domain of connexin43 ; GLUT-3 ; glucose transporter-3 ; GSC ; glioma stem cells ; HIF ; hypoxia-inducible factor ; HK2 ; type II hexokinase ; IDP ; intrinsically disordered protein ; IDR ; intrinsically disordered region ; MAPK ; mitogen-activated protein kinases ; miRNA ; microRNA ; MTOC ; microtubule organizing center ; PDZ ; postsynaptic density 95/disk-large/zona occludens ; pRb ; retinoblastoma protein ; PTEN ; phosphatidylinositol 34 ; 5-trisphosphate 3-phosphatase and dual-spe

刊名：Neuroscience

出版年：2016

作者：Tsuey-Ming Chen^a ; Frank S. Czerwiec^b ; David Puett^c ; ^{puett@uga.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：AP-1 ; activator protein 1 ; BSA ; bovine serum albumin ; CREB ; cAMP response element binding protein ; db-cAMP ; dibutryl cAMP ; EGF ; epidermal growth factor ; EGFR ; epidermal growth factor receptor ; ERG ; early response gene ; ERK1/2 ; extracellular signal regulated kinases ; EPAC ; exchange protein directly activated by cAMP ; hCG ; human chorionic gonadotropin ; IBMX ; isobutylmethylxanthine ; IP3 ; 14 ; 5-inositol trisphosphate ; LHR ; luteinizing hormone receptor (also binds hCG) ; 4α-PE ; 4α-phorbol 12 ; 13-dideca

刊名：Biochemistry and Biophysics Reports

出版年：2016

作者：Gayane Machkalyan^a ; Phan Trieu^a ; Darlaine Pé ; trin^a ; Terence E. Hé ; bert^a ; ^{terence.hebert@mcgill.ca" class="auth_mail" title="E-mail the corresponding author} ; Gregory J. Miller^a ; ^b ; ^{MILLERGJ@cua.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Arp2/3 ; actin-related protein 2/3 complex ; CBD ; calmodulin binding domain ; DIPP ; diphosphoryl inositol polyphosphate phosphohydrolase ; EXOC1&ndash8 ; exocyst complex component 1&ndash8 ; GST ; Glutathione-S-transferase ; HA ; hemagglutinin ; InsPP ; inositol pyrophosphate ; Ins (14 ; 5)P3 ; inositol 14 ; 5-trisphosphate ; InsP8 ; bis-diphosphoinositol tetrakisphosphate ; IP6K ; inositol hexakisphosphate kinases ; PH ; pleckstrin homology ; PIP5K ; phosphatidylinositol 4-phosphate 5-kinase ; PIP4K ; phosphatidylino

刊名：Cellular Signalling

出版年：2016

作者：Roberta Imperatore^a ; Letizia Palomba^b ; Giovanna Morello^a ; Alessandro Di Spiezio^c ; Fabiana Piscitelli^a ; Vincenzo Di Marzo^a ; Luigia Cristino^a ; ^{luigia.cristino@icb.cnr.it" class="auth_mail" title="E-mail the corresponding author}

关键词：2-AG ; 2-arachidonoylglycerol ; ACEA ; arachidonyl-2-chloroethylamide ; AgRP ; agouti-related peptide ; CB1R ; cannabinoid receptor ; CHO ; chinese hamster ovary cells ; DAG ; diacylglycerol ; DAGL ; diacylglycerol lipase ; ERK ; extracellular-signal-regulated kinases ; FRET ; fluorescence resonance energy transfer ; GPCRs ; G protein coupled receptors ; IP3 ; inositol trisphosphate ; NPY ; neuropeptide Y ; OX-A ; orexin-A ; OX-1R ; orexin 1 receptor ; PLC ; phospholipase C

刊名：Pharmacological Research

出版年：2016