作者：David J. Irwin (1) (2)
Nigel J. Cairns (4)
Murray Grossman (2)
Corey T. McMillan (2)
Edward B. Lee (3)
Vivianna M. Van Deerlin (1)
Virginia M.-Y. Lee (1)
John Q. Trojanowski (1)

1. Department of Pathology and Laboratory Medicine ; Center for Neurodegenerative Disease Research ; Institute on Ageing ; University of Pennsylvania School of Medicine ; HUP Maloney 3rd Floor ; 36th and Spruce Streets ; Philadelphia ; PA ; 19104-4283 ; USA
2. Department of Neurology ; Penn Frontotemporal Degeneration Center ; University of Pennsylvania ; Philadelphia ; PA ; 19104 ; USA
4. Department of Pathology and Immunology ; Washington University School of Medicine ; St. Louis ; MO ; 63110 ; USA
3. Translational Neuropathology Research Laboratory ; Department of Pathology and Laboratory Medicine ; Perelman School of Medicine ; University of Pennsylvania ; Philadelphia ; PA ; 19104 ; USA

关键词：FTLD ; TDP ; 43 ; Tau ; ALS ; C9orf72 ; GRN ; MAPT

刊名：Acta Neuropathologica

出版年：2015

作者：Fei Chen (1)
Xueqian Zhuang (1)
Liangyu Lin (1)
Pengfei Yu (1)
Ying Wang (1)
Yufang Shi (1) (2)
Guohong Hu (1)
Yu Sun (1) (3) (4) (5)

1. Key Laboratory of Stem Cell Biology ; Institute of Health Sciences ; Shanghai Institutes for Biological Sciences ; Chinese Academy of Sciences/Shanghai Jiaotong University School of Medicine ; Shanghai ; 200031 ; China
2. Soochow Institutes for Translational Medicine ; Soochow University ; Suzhou ; 215123 ; China
3. VA Seattle Medical Center ; Seattle ; WA ; 98108 ; USA
4. Department of Medicine ; University of Washington ; Seattle ; WA ; 98195 ; USA
5. Institute of Health Sciences ; Shanghai Institutes for Biological Sciences (SIBS) ; Chinese Academy of Sciences (CAS) and Shanghai Jiaotong University School of Medicine (SJTUSM) ; 320 Yue Yang Road ; Biological Research Building A ; Shanghai ; 200031 ; China

关键词：Acquired resistance ; Clinical oncology ; Combination therapy ; Distant metastasis ; Immunomodulation ; Targeting strategy ; Therapeutic intervention ; Translational medicine ; Tumor microenvironment

刊名：BMC Medicine

出版年：2015

作者：McKinsey L. Goodenberger (1)
Brittany C. Thomas (2)
Karen E. Wain (1)

1. Division of Cytogenetics ; Department of Laboratory Medicine and Pathology ; Mayo Clinic ; Rochester ; MN ; USA
2. Division of Molecular Genetics ; Department of Laboratory Medicine and Pathology ; Mayo Clinic ; Rochester ; MN ; USA

关键词：Laboratory genetic counseling ; Laboratory genetic counselor ; Counseling skills ; Training program curriculum

刊名：Journal of Genetic Counseling

出版年：2015

作者：Xin Wang (1) (2)
Adrian M. Dubuc (1) (2)
Vijay Ramaswamy (1) (2) (3)
Stephen Mack (1) (2)
Deena M. A. Gendoo (4)
Marc Remke (1) (2)
Xiaochong Wu (1)
Livia Garzia (1)
Betty Luu (1)
Florence Cavalli (1)
John Peacock (1) (2)
Borja L贸pez (1)
Patryk Skowron (1) (2)
David Zagzag (5)
David Lyden (6)
Caitlin Hoffman (1) (7)
Yoon-Jae Cho (8)
Charles Eberhart (9)
Tobey MacDonald (10)
Xiao-Nan Li (11)
Timothy Van Meter (12)
Paul A. Northcott (13)
Benjamin Haibe-Kains (14) (4)
Cynthia Hawkins (15)
James T. Rutka (7)
Eric Bouffet (3)
Stefan M. Pfister (13)
Andrey Korshunov (16)
Michael D. Taylor (1) (7)

1. Developmental and Stem Cell Biology Program ; The Hospital for Sick Children ; University of Toronto ; Toronto ; ON ; Canada
2. Department of Laboratory Medicine and Pathobiology ; University of Toronto ; Toronto ; ON ; Canada
3. Division of Haematology/Oncology ; Hospital for Sick Children ; Toronto ; ON ; Canada
4. Bioinformatics and Computational Genomics Laboratory ; Princess Margaret Cancer Centre ; University Health Network ; Toronto ; ON ; Canada
5. Departments of Pathology and Neurosurgery ; NYU Langone Medical Center ; New York ; NY ; USA
6. Departments of Pediatrics ; Cell and Developmental Biology ; Weill Medical College of Cornell University ; New York ; NY ; USA
7. Division of Neurosurgery ; Hospital for Sick Children ; 555 University Ave ; Ste 1503 ; Toronto ; ON ; M5C 1X8 ; Canada
8. Department of Neurology and Neurological Sciences ; Stanford University School of Medicine ; Stanford ; CA ; USA
9. Departments of Pathology ; Ophthalmology and Oncology ; John Hopkins University School of Medicine ; Baltimore ; MD ; USA
10. Pediatric Neuro-Oncology Program ; Emory University School of Medicine ; Atlanta ; GA ; USA
11. Department of Pediatrics ; Brain Tumor Program ; Children鈥檚 Cancer Center ; Baylor College of Medicine ; Houston ; TX ; USA
12. Department of Pediatrics ; Virginia Commonwealth University School of Medicine ; Richmond ; VA ; USA
13. Division of Pediatric Neurooncology ; Department of Pediatric Hematology and Oncology ; German Cancer Consortium (DKTK) ; German Cancer Research Center (DKFZ) ; Heidelberg University Hospital ; Heidelberg ; Germany
14. Department of Medical Biophysics ; University of Toronto ; Toronto ; ON ; Canada
15. Department of Pathology ; Hospital for Sick Children ; Toronto ; ON ; Canada
16. Clinical Cooperation Unit Neuropathology ; German Cancer Research Center (DKFZ) ; Heidelberg ; Germany

关键词：Medulloblastoma ; Metastasis ; Molecular subgroups ; Integrative genomics ; Gene expression ; DNA methylation

刊名：Acta Neuropathologica

出版年：2015

作者：Yu Gu (1)
Tianxiang Chen (2)
Suzhen Fu (3)
Xin Sun (4)
Lingyan Wang (5)
Jian Wang (5)
Yingfeng Lu (3)
Songming Ding (6)
Guodong Ruan (7)
Lisong Teng (1)
Min Wang (1)

1. Department of Surgical Oncology ; First Affiliated Hospital ; College of Medicine ; Zhejiang University ; Hangzhou ; China
2. Department of Thoracic Surgery ; First Affiliated Hospital ; College of Medicine ; Zhejiang University ; Hangzhou ; China
3. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases ; Department of Infectious Diseases ; First Affiliated Hospital ; College of Medicine ; Zhejiang University ; Hangzhou ; China
4. Division of Neurobiology ; Department of Psychiatry and Behavioral Sciences ; Johns Hopkins University School of Medicine ; Baltimore ; USA
5. Biomedical Research Center ; Zhongshan Hospital ; Fudan University ; Shanghai ; China
6. Division of Hepatobiliary and Pancreatic Surgery ; Department of Surgery ; First Affiliated Hospital ; College of Medicine ; Zhejiang University ; Hangzhou ; China
7. Department of Oncology ; The Second Hospital of Shaoxing ; Shaoxing ; China

关键词：Amino acid profile ; Plasma ; Metabolism ; Cancer ; Perioperation

刊名：Journal of Translational Medicine

出版年：2015

作者：David Buchbinder (1) (12)
Rebecca Baker (2)
Yu Nee Lee (3)
Juan Ravell (2)
Yu Zhang (4)
Joshua McElwee (5)
Diane Nugent (1)
Emily M. Coonrod (7)
Jacob D. Durtschi (7)
Nancy H. Augustine (7) (8)
Karl V. Voelkerding (7) (8)
Krisztian Csomos (11)
Lindsey Rosen (2)
Sarah Browne (2)
Jolan E. Walter (11) (6)
Luigi D. Notarangelo (6)
Harry R. Hill (10) (7) (8) (9)
Attila Kum谩novics (7) (8)

1. Pediatrics / Hematology ; CHOC Children鈥檚 Hospital鈥擴C Irvine ; Orange ; CA ; USA
12. Division of Hematology ; CHOC Children鈥檚 Hospital ; 1201 La Veta ; Orange ; CA ; 92868 ; USA
2. Laboratory of Clinical Infectious Diseases ; NIAID ; NIH ; Bethesda ; MD ; USA
3. Division of Immunology ; Boston Children鈥檚 Hospital Harvard Medical School ; Boston ; MA ; USA
4. Laboratory of Host Defenses ; National Institutes of Allergy and Infectious Diseases ; NIH ; Bethesda ; MD ; USA
5. Merck Research Laboratories ; Merck & Co. Inc. ; Boston ; MA ; USA
7. ARUP Institute for Clinical and Experimental Pathology ; Salt Lake City ; UT ; USA
8. Department of Pathology ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA
11. Pediatric Allergy & Immunology and the Center for Immunology and Inflammatory Diseases ; Massachusetts General Hospital ; Harvard Medical School ; Boston ; MA ; USA
6. Division of Immunology ; Boston Children鈥檚 Hospital ; Boston ; MA ; USA
10. Department of Pediatrics ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA
9. Department of Internal Medicine ; University of Utah School of Medicine ; Salt Lake City ; UT ; USA

关键词：RAG1 ; RAG deficiency ; primary immunodeficiency ; severe combined immune deficiency ; common variable immunodeficiency disorder ; exome sequencing ; gene panel

刊名：Journal of Clinical Immunology

出版年：2015

作者：Haiqiang Dou (1) (2) (3) (4) (5)
Changhe Wang (1) (2) (3) (4) (5)
Xi Wu (1) (2) (3) (4) (5)
Lijun Yao (1) (2) (3) (4) (5)
Xiaoyu Zhang (1) (2) (3) (4) (5)
Sasa Teng (1) (2) (3) (4) (5)
Huadong Xu (1) (2) (3) (4) (5)
Bin Liu (1) (2) (3) (4) (5)
Qihui Wu (1) (2) (3) (4) (5)
Quanfeng Zhang (1) (2) (3) (4) (5)
Meiqin Hu (1) (2) (3) (4) (5)
Yeshi Wang (1) (2) (3) (4) (5)
Li Wang (1) (2) (3) (4) (5)
Yi Wu (1) (3)
Shujiang Shang (1) (2) (3) (4) (5)
Xinjiang Kang (1) (2) (3) (4) (5)
Lianghong Zheng (1) (2) (3) (4) (5)
Jin Zhang (6)
Matthieu Raoux (7)
Jochen Lang (7)
Qing Li (8)
Jing Su (8)
Xiao Yu (8)
Liangyi Chen (1) (3)
Zhuan Zhou (1) (2) (3) (4) (5)

1. Institute of Molecular Medicine ; Peking University ; 5 Yiheyuan Road ; Beijing ; 100871 ; China
2. State Key Laboratory of Biomembrane and Membrane Biotechnology ; Peking University ; Beijing ; People鈥檚 Republic of China
3. Beijing Key Laboratory of Cardiometabolic Molecular Medicine ; Peking University ; Beijing ; People鈥檚 Republic of China
4. PKU-IDG/McGovern Institute for Brain Research ; Peking University ; Beijing ; People鈥檚 Republic of China
5. Peking-Tsinghua Centre for Life Sciences ; Peking University ; Beijing ; People鈥檚 Republic of China
6. Department of Pharmacology and Molecular Sciences ; The Johns Hopkins University School of Medicine ; Baltimore ; MD ; USA
7. Universit茅 de Bordeaux I Institut Europ茅en de Chimie et Biologie UMR CNRS 5248 ; Bordeaux ; France
8. Department of Physiology ; Shandong University School of Medicine ; 44 Wenhua Xi Road ; Jinan ; 250012 ; People鈥檚 Republic of China

关键词：Adenylyl cyclase 8 ; Ca2+ ; Pancreatic beta cell ; Protein kinase A ; Vesicle pool

刊名：Diabetologia

出版年：2015

作者：Roger V Lebo (1) (2)
Vijay S Tonk (3) (4)

1. Department of Pathology and Laboratory Medicine ; Akron Children鈥檚 Hospital ; One Perkins Square ; Akron ; OH ; 44308-1062 ; USA
2. Northeast Ohio Medical University ; Rootstown ; OH ; USA
3. Department of Pediatrics ; Texas Tech University Health Science Center ; 4th Street 3601 ; Lubbock ; TX ; 79416 ; USA
4. Texas Tech University Health Sciences Center ; El Paso ; TX ; USA

关键词：Most frequent diseases ; Targeted patient categories ; Disease identification ; Test accuracy

刊名：Journal of Translational Medicine

出版年：2015

作者：J. A. Chenoweth (1)
R. R. Gerona (4)
J. B. Ford (1)
M. E. Sutter (1)
J. S. Rose (2)
T. E. Albertson (3)
S. O. Clarke (2)
K. P. Owen (1)

1. Department of Emergency Medicine ; University of California ; Davis Medical Center and VA Northern California Health Care System ; 4150 V Street ; Suite 2100 ; Sacramento ; CA ; 95817 ; USA
4. Department of Laboratory Medicine ; University of California ; San Francisco ; 513 Parnauss Ave ; San Francisco ; CA ; 94143 ; USA
2. Department of Emergency Medicine ; University of California ; Davis Medical Center ; 4150 V Street ; Suite 2100 ; Sacramento ; CA ; 95817 ; USA
3. Division of Pulmonary ; Critical Care ; and Sleep Medicine ; University of California ; Davis Medical Center and VA Northern California Health Care System ; 4150 V Street Suite 2400 ; Sacramento ; CA ; 95817 ; USA

关键词：Gacyclidine ; Dissociative toxicity ; Phencyclidine derivative

刊名：Journal of Medical Toxicology

出版年：2015

作者：Ana M Misic (1)
Meghan F Davis (2)
Amanda S Tyldsley (1)
Brendan P Hodkinson (1)
Pam Tolomeo (3)
Baofeng Hu (4)
Irving Nachamkin (4)
Ebbing Lautenbach (3) (5)
Daniel O Morris (6)
Elizabeth A Grice (1)

1. Department of Dermatology ; Perelman School of Medicine ; University of Pennsylvania ; 421 Curie Blvd ; 1007 Biomedical Research Building ; Philadelphia ; PA ; 19104 ; USA
2. Department of Environmental Health Sciences ; Johns Hopkins Bloomberg School of Public Health ; Baltimore ; MD ; USA
3. Department of Biostatistics and Epidemiology ; Perelman School of Medicine ; University of Pennsylvania ; Philadelphia ; PA ; USA
4. Department of Pathology and Laboratory Medicine ; Perelman School of Medicine ; University of Pennsylvania ; Philadelphia ; PA ; USA
5. Department of Medicine ; Perelman School of Medicine ; University of Pennsylvania ; Philadelphia ; PA ; USA
6. Department of Clinical Studies ; School of Veterinary Medicine ; University of Pennsylvania ; Philadelphia ; PA ; USA

关键词：16S rRNA ; Methicillin ; resistant Staphylococcus aureus (MRSA) ; Microbiome ; Pet ; Staphylococcus ; Skin and soft tissue infection (SSTI)

刊名：Microbiome

出版年：2015