作者：Claudio Fozza ; ^{cfozza@uniss.it} ; Francesca Barraqueddu ; Giovanna Corda ; Salvatore Contini ; Patrizia Virdis ; Fausto Dore ; Silvana Bonfigli ; Maurizio Longinotti

关键词：T-cell receptor (TCR) repertoire ; Complementarity determining region (CDR3) ; Spectratyping ; Immune-mediated disorders ; Infective diseases ; Neoplasms

刊名：Journal of Immunological Methods

出版年：2017

作者：Tomoaki Noguchi ; Yuichi Nishida ; Keiji Takizawa ; Yue Cui ; Koki Tsutsumi ; Takashi Hamada ; Yoshisuke Nishi ; ^{y_nishi@nagahama-i-bio.ac.jp}

关键词：CD ; Circular Dichroism ; ELISA ; enzyme-linked immunosorbent assay ; TCDR ; three-step cold dialysis refolding ; OHDR ; one-step hot dialysis refolding ; OCDR ; one-step cold dialysis refolding ; CDR ; complementarity determining region ; HV ; hypervariable region ; CBB ; Coomassie Brilliant Blue ; IPTG ; isopropyl β-D-1-thiogalactopyranoside ; SDS ; sodium dodecyl sulfate ; PAGE ; polyacrylamide gel electrophoresis ; Gdn-HCl ; guanidinium chloride ; DTT ; dithiothreitol ; 2-ME ; 2-mercaptoethanol ; EDTA ; ethylenediaminet

刊名：Journal of Immunological Methods

出版年：2017

作者：Mark B. Swindells¹ ; Craig T. Porter² ; Matthew Couch² ; Jacob Hurst² ; ⁴ ; K.R. Abhinandan² ; ⁵ ; Jens H. Nielsen³ ; Gary Macindoe³ ; James Hetherington³ ; Andrew C.R. Martin² ; ^{andrew@bioinf.org.uk} ; ^{andrew.martin@ucl.ac.uk}

关键词：CDR ; complementarity-determining region ; PDB ; Protein Data Bank ; IMGT ; Immunogenetics Database ; EMBL-ENA ; European Molecular Biology Laboratory European Nucleotide Archive

刊名：Journal of Molecular Biology

出版年：2017

作者：Tomonori Osajima ; Tyuji Hoshino ; ^{hoshino@chiba-u.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：Antigen-antibody complex ; Complementarity determining region ; Binding free energy ; Molecular dynamics simulation ; Energetic contribution ; Amino acid residues

刊名：Computational Biology and Chemistry

出版年：2016

作者：Changlong Guo ; MD ; PhD¹ ; ^&lowast ; ; Qidi Wang ; MD ; PhD¹ ; ^&lowast ; ; Xiaofang Cao ; MD¹ ; ^{mybrother1984@163.com" class="auth_mail" title="E-mail the corresponding author} ; Ying Yang ; MD ; PhD¹ ; Xin Liu ; PhD¹ ; ² ; Lisha An ; MD¹ ; Ruikun Cai ; PhD¹ ; Meng Du ; MD¹ ; ³ ; Guangyu Wang ; MD¹ ; Yue Qiu ; MD¹ ; ³ ; Zuoqi Peng ; MD¹ ; Jian Han ; MD ; PhD⁴ ; Shuhua Ni ; PhD⁵ ; Xuerui Tan ; MD ; PhD⁵ ; Li Jin ; MD⁶ ; Song Yu ; MD⁷ ; Huiying Wang ; MD⁸ ; Chunlin Wang ; PhD¹ ; ⁹ ; Xingyu Wang ; MD ; PhD¹ ; ² ; Xu Ma ; MD ; PhD¹ ; ³

关键词：umbilical cord blood ; high-throughput sequencing ; TRB-/IgH-CDR3 repertoires

刊名：The Journal of Pediatrics

出版年：2016

作者：Mary H. Foster^a ; ^b ; ^c ; ^{mary.h.foster@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author} ; ^{mhfoster@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Elizabeth S. Buckley^a ; ^{elizabeth.buckley@duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Benny J. Chen^a ; ^c ; ^{benny.chen@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Kwan-Ki Hwang^a ; ^d ; ^{kwan-ki.hwang@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author} ; Amy G. Clark^a ; ^b ; ^{amy.clark@duke.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Ag ; antigen ; bnAb ; broadly neutralizing anti-HIV Ig ; CLL ; chronic lymphocytic leukemia ; EBV ; Epstein Barr virus ; GBM ; glomerular basement membrane ; GN ; glomerulonephritis ; GP ; Goodpasture ; GPS ; GP syndrome ; HC ; heavy chain ; HCDR3 ; heavy chain complementarity determining region3 ; HSC ; hematopoietic stem cells ; IMGT ; ImMunoGeneTics information system ; LC ; light chain ; mAb ; monoclonal antibody ; NC1 ; non-collagenous-1 (domain) ; NSG ; NOD-scid-gamma ; V ; variable

刊名：Molecular Immunology

出版年：2016

作者：Yaming Shao¹ ; ^&dagger ; ; Hao Huang² ; ^&dagger ; ; Daoming Qin³ ; Nan-Sheng Li¹ ; Akiko Koide¹ ; ⁴ ; Jonathan P. Staley³ ; Shohei Koide¹ ; ⁴ ; Anthony A. Kossiakoff¹ ; Joseph A. Piccirilli¹ ; ² ; ^{jpicciri@uchicago.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CDR ; complementarity-determining region ; ncRNA ; non-coding RNA ; ssRNA ; single-stranded RNA ; Deoxy R ; deoxynucleotide version of the R strand ; MR ; molecular replacement ; PBS ; phosphate-buffered saline ; R.T. ; room temperature

刊名：Journal of Molecular Biology

出版年：2016

作者：Natalia Girola^a ; Alisson L. Matsuo^b ; Carlos R. Figueiredo^a ; Mariana H. Massaoka^a ; Camyla F. Farias^a ; Denise C. Arruda^c ; Ricardo A. Azevedo^d ; Hugo P. Monteiro^e ; Pedro T. Resende-Lara^f ; Rodrigo L.O.R. Cunha^g ; Luciano Polonelli^h ; Luiz R. Travassos^a ; ⁱ ; ^{luiztravassos@gmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Antitumor peptides ; Antibody CDRs ; Melanoma ; Cell migration ; Metastasis ; Hsp90 ; G-protein coupled receptor

刊名：Peptides

出版年：2016

作者：Mahmood A. Al Kindi^a ; Alex D. Colella^a ; ^b ; Tim K. Chataway^b ; Michael W. Jackson^a ; Jing J. Wang^a ; ¹ ; ^{jing.wang@flinders.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Tom P. Gordon^a ; ¹ ; ^{t.gordon@flinders.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：aa ; amino acid ; D ; diversity ; 2-DE ; two-dimensional gel electrophoresis ; H-chain ; heavy chain ; HCDR3 ; heavy chain complementarity determining region 3 ; HPLC ; high-performance liquid chromatography ; Ig ; immunoglobulin ; J ; joining ; L-chain ; light chain ; MRM ; multiple reactions monitoring ; MS ; mass spectrometer ; NGS ; next generation sequencing ; Q-TOF ; quadrupole-time of flight ; SLE ; systemic lupus erythematosus ; SS ; Sjö ; gren's syndrome ; V ; variable

刊名：Autoimmunity Reviews

出版年：2016

作者：Janita Lö ; vgren^a ; ^{janita.lovgren@utu.fi" class="auth_mail" title="E-mail the corresponding author} ; ^{janita.lovgren@pp.inet.fi" class="auth_mail" title="E-mail the corresponding author} ; Juha-Pekka Pursiheimo^b ; ¹ ; Mikko Pyykkö ; ^a ; Jussi Salmi^b ; Urpo Lamminmä ; ki^a

关键词：CAD ; coronary artery disease ; CDR ; complementarity determining region ; HDL ; high density lipoprotein ; LDL ; low density lipoprotein ; NGS ; next generation sequencing ; scFv ; single-chain variable fragment

刊名：New Biotechnology

出版年：2016