作者：Keisuke Kakisaka ; ^{keikaki@iwate-med.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Kojiro Kataoka ; Yuji Suzuki ; Yohei Okada ; Yuichi Yoshida ; Hidekatsu Kuroda ; Yasuhiro Takikawa

关键词：ALF ; acute liver failure ; ALI ; acute liver injury ; AIH ; autoimmune hepatitis ; AIH-ALF ; AIH-induced ALF ; AIH-ALI ; AIH-induced ALI ; DILI ; drug-induced liver injury ; DILI-ALF ; DILI-induced ALF ; DILI-ALI ; DILI-induced ALI ; HAV ; hepatitis A virus ; HCV ; hepatitis C virus ; HE ; hepatic encephalopathy ; HEV ; hepatitis E virus ; MELD ; model for end-stage liver disease ; PT-INR ; prothrombin time-international normalized ratio.

刊名：Cytokine

出版年：2016

作者：Inmaculada Medina-Caliz¹ ; ^a ; ^&dagger ; ; Mercedes Robles-Diaz¹ ; ^a ; ^&dagger ; ; Beatriz Garcia-Muñ ; oz¹ ; Camilla Stephens¹ ; ^a ; Aida Ortega-Alonso¹ ; Miren Garcia-Cortes¹ ; ^a ; Andres Gonzá ; lez-Jimenez¹ ; Judith A. Sanabria-Cabrera¹ ; Inmaculada Moreno¹ ; ^a ; M. Carmen Fernandez² ; Manuel Romero-Gomez³ ; ^a ; Jose M. Navarro⁴ ; Ana Mª ; Barriocanal⁵ ; Eva Montane⁵ ; Hacibe Hallal⁶ ; Sonia Blanco⁷ ; German Soriano⁸ ; ^a ; Eva M. Roman⁸ ; ^a ; Elena Gó ; mez-Dominguez⁹ ; Agustin Castiella¹⁰ ; Eva M. Zapata¹⁰ ; Miguel Jimenez-Perez¹¹ ; Jose M. Moreno¹² ; Ana Aldea-Perona¹³ ; Manuel Herná ; ndez-Guerra¹⁴ ; Martin Prieto¹⁵ ; ^a ; Miguel E. Zoubek¹ ; Neil Kaplowitz¹⁶ ; M. Isabel Lucena¹ ; ^a ; ^{lucena@uma.es" class="auth_mail" title="E-mail the corresponding author} ; Raul J. Andrade¹ ; ^a ; on behalf of the Spanish DILI registry

关键词：DILI ; drug-induced liver injury ; ALP ; alkaline phosphatase ; TB ; total bilirubin ; ULN ; upper limit of normal ; AST ; aspartate aminotransferase ; ALT ; alanine aminotransferase ; INR ; international normalized ratio ; R ; ratio ; HC ; hepatocellular ; Chol ; cholestatic ; Mix ; mixed ; CIOMS ; Council for International Organizations of Medical Sciences ; RUCAM ; Roussel Uclaf causality assessment method ; NASH ; non-alcoholic steatohepatitis

刊名：Journal of Hepatology

出版年：2016

作者：Lysiane Richert^a ; ^h ; ^{l.richert@kaly-cell.com" class="auth_mail" title="E-mail the corresponding author} ; Audrey Baze^a ; ^{a.baze@kaly-cell.com" class="auth_mail" title="E-mail the corresponding author} ; Cé ; line Parmentier^a ; ^{c.parmentier@kaly-cell.com" class="auth_mail" title="E-mail the corresponding author} ; Helga H.J. Gerets^b ; ^{helga.gerets@ucb.com" class="auth_mail" title="E-mail the corresponding author} ; Rowena Sison-Young^c ; ^{Rowena.Sison-Young@liverpool.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Martina Dorau^d ; ^{Martina.Dorau@sanofi.com" class="auth_mail" title="E-mail the corresponding author} ; Cerys Lovatt^e ; ^{cerys.a.lovatt@gsk.com" class="auth_mail" title="E-mail the corresponding author} ; Andreas Czich^d ; ^{Andreas.Czich@sanofi.com" class="auth_mail" title="E-mail the corresponding author} ; Christopher Goldring^c ; ^{C.E.P.Goldring@liverpool.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; B. Kevin Park^c ; ^{B.K.Park@liv.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Satu Juhila^f ; ^{satu.juhila@orionpharma.com" class="auth_mail" title="E-mail the corresponding author} ; Alison J. Foster^g ; ^{Alison.Foster2@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author} ; Dominic P. Williams^g ; ^{Dominic.P.Williams@astrazeneca.com" class="auth_mail" title="E-mail the corresponding author}

关键词：DILI ; drug-induced liver injury ; NPC ; non-parenchymal cells ; 2D-sw ; 2D-sandwich ; SM ; safety margin ; MT ; microtissue ; TC ; training compound

刊名：Toxicology Letters

出版年：2016

作者：Francisco Javier Cubero¹ ; ^{fcubero@ukaachen.de" class="auth_mail" title="E-mail the corresponding author} ; Miguel Eugenio Zoubek¹ ; Wei Hu¹ ; Jin Peng¹ ; Gang Zhao¹ ; Yulia A. Nevzorova¹ ; Malika Al Masaoudi¹ ; Lars P. Bechmann² ; Mark V. Boekschoten³ ; Michael Muller⁴ ; Christian Preisinger⁵ ; Nikolaus Gassler⁶ ; Ali E. Canbay² ; Tom Luedde¹ ; Roger J. Davis⁷ ; Christian Liedtke¹ ; Christian Trautwein¹ ; ^{ctrautwein@ukaachen.de" class="auth_mail" title="E-mail the corresponding author}

关键词：APAP ; Mouse Model ; Gene Regulation ; Pharmacologic Treatment

刊名：Gastroenterology

出版年：2016

作者：Binxia Chang^a ; ¹ ; Baosen Li^a ; ¹ ; Ang Huang^a ; Ying Sun^a ; Guangju Teng^a ; Xiaoxia Wang^c ; Suthat Liangpunsakul^b ; Jin Li^c ; ^{lijin302@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Zhengsheng Zou^a ; ^{zszou302@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Non-infectious liver disease ; Alcoholic liver disease ; Autoimmune liver disease ; Drug-induced liver injury ; Non-alcoholic fatty liver disease

刊名：Alcohol

出版年：2016

作者：Helen Garside ; Karen F. Marcoe ; Jessica Chesnut-Speelman ; Alison J. Foster ; Daniel Muthas ; J. Gerry Kenna ; Usha Warrior ; Joanne Bowes ; James Baumgartner

关键词：Hepatotoxicity ; Imaging ; Metabolism ; Hepatocytes

刊名：Toxicology in Vitro

出版年：March, 2014

作者：Dotan Uzi ; Liran Barda ; Viviana Scaiewicz ; Maya Mills ; Tobias Mueller ; Agueda Gonzalez-Rodriguez ; Angela M. Valverde ; Takao Iwawaki ; Yaacov Nahmias ; Ramnik Xavier ; Ray T. Chung ; Boaz Tirosh ; Oren Shibolet

关键词：DILI ; drug induced liver injury ; APAP ; acetaminophen (N-acetyl-p-aminophenol) ; NAPQI ; N-acetylbenzoquinoneimine ; GSH ; glutathione ; ER ; endoplasmic reticulum ; UPR ; unfolded protein response ; ALI ; acute liver injury ; ROS ; reactive oxygen species ; ALT ; alani

刊名：Journal of Hepatology

出版年：2013

作者：Kerry M. Wooding^a ; ^b ; Richard J. Auchus^c ; ^{rauchus@med.umich.edu}

关键词：APCI ; atmospheric pressure chemical ionization ; APPI ; atmospheric pressure photochemical ionization ; CDC ; Center for Disease Control ; CI ; chemical ionization ; CID ; collision-induced dissociation ; CRPC ; castration-resistant prostate cancer ; ELISA ; enzyme-l

刊名：Molecular and Cellular Endocrinology

出版年：2013

作者：Gufran Beig ; Dilip M. Chate ; Sachin. D. Ghude ; A.S. Mahajan ; R. Srinivas ; K. Ali ; S.K. Sahu ; N. Parkhi ; D. Surendran ; H.R. Trimbake

关键词：Commonwealth Games 2010 ; Ozone ; Nitrogen oxides ; Particulate matter ; Air quality ; SAFAR

刊名：Atmospheric Environment

出版年：2013

作者：Adam D. Farmer ; Alison Brind

关键词：cholestatic ; direct toxic effect ; drug-induced liver injury ; drug metabolism ; genetic susceptibility ; hepatocellular ; immunological

刊名：Medicine

出版年：2011