作者：Yinan Li^a ; ^&dagger ; ; Nilgun Donmez^a ; ^b ; ^&dagger ; ; Cenk Sahinalp^a ; ^b ; Ning Xie^a ; Yuwei Wang^c ; Hui Xue^c ; Fan Mo^a ; Himisha Beltran^d ; Martin Gleave^a ; Yuzhuo Wang^a ; ^c ; Colin Collins^a ; ^b ; ^e ; ^&Dagger ; ; ^{ccollins@prostatecentre.com} ; Xuesen Dong^a ; ^&Dagger ; ; ^{xdong@prostatecentre.com}

关键词：Neuroendocrine prostate cancer ; AR inhibition ; SRRM4 ; Alternative RNA splicing

刊名：European Urology

出版年：2017

作者：K.R. Mewes^a ; ^{karsten.mewes@henkel.com" class="auth_mail" title="E-mail the corresponding author} ; A. Fischer^a ; N.N. Zö ; ller^b ; V. Laubach^b ; A. Bernd^b ; A. Jacobs^c ; A. van Rompay^c ; M. Liebsch^d ; R. Pirow^d ; D. Petersohn^a

关键词：1-BH ; 1-bromohexane ; ALI ; Air-Liquid Interface ; BLR ; Between-laboratory-reproducibility ; CyA ; Cyclamen aldehyde ; D-PBS ; Dulbecco's phosphate-buffered saline ; ECETOC ; European Centre for Ecotoxicology and Toxicology ; EURL-ECVAM ; European Union Reference Laboratory for the Validation of Alternative Methods ; ET50 ; effective time at 50% viability ; EU ; European Union ; GC/MS ; gas chromatography/mass spectroscopy ; MTT ; 3-(4 ; 5-dimethylthiazo-2-yl)-2 ; 5-diphenyltetrazoliumbromide ; NC ; negative control ; OD

刊名：Toxicology in Vitro

出版年：2016

作者：Yurika Fujita ; Toshio Kasamatsu ; Naohiro Ikeda ; Naohiro Nishiyama ; Hiroshi Honda ; ^{honda.hiroshi@kao.co.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：CA ; chromosomal aberration ; DB ; database ; ECVAM ; The European Centre for the Validation of Alternative Methods ; IWGT ; International Workshops on Genotoxicity Testing ; JEC ; Japan Existing Chemical ; LOGEL ; lowest observed genotoxicity effect level ; MN ; micronucleus ; OECD ; Organization for Economic Co-operation and Development ; RCC ; relative cell count ; RICC ; relative increase in cell count ; RPD ; relative population doubling ; PD ; population doubling ; TG ; test guideline

刊名：Mutation Research/Genetic Toxicology and Environmental Mutagenesis

出版年：2016

作者：Lucia Vergauwen^a ; ^{lucia.vergauwen@uantwerpen.be" class="auth_mail" title="E-mail the corresponding author} ; Stine N. Schmidt^b ; Evelyn Stinckens^a ; Walid Maho^c ; Ronny Blust^d ; Philipp Mayer^b ; Adrian Covaci^c ; Dries Knapen^a

关键词：AhR ; aryl hydrocarbon receptor ; AOP ; adverse outcome pathway ; C ; (regular) control ; CBR(LIP)50 ; (lipid normalized) critical body residue ; Ea50 ; effective chemical activity ; EBR(LIP)50 ; (lipid normalized) effective body residue ; ED50 ; effective dose ; EI ; electron ionization mode ; EURL ECVAM ; European Union Reference Laboratory for alternatives to animal testing &ndash ; European Centre for the Validation of Alternative Methods ; FET ; Fish Embryo Acute Toxicity ; HOC ; hydrophobic organic compound ; Hp

刊名：Chemosphere

出版年：2015

作者：Katarzyna Wroblewska^a ; Małgorzata Kucinska^b ; Marek Murias^b ; Janina Lulek^a ; ^{jlulek@ump.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：Eye drops ; Choline salicylate ; Short time exposure (STE) in vitro tests ; MTT ; Neutral Red Uptake

刊名：Journal of the Saudi Pharmaceutical Society

出版年：2015

作者：Anna Koryakina ^{anna.koryakina@bluewin.ch" class="auth_mail} ; Esther Frey ^{esther.frey@novartis.com" class="auth_mail} ; Peter Bruegger ; ^{peter.bruegger@novartis.com" class="auth_mail}

关键词：BET ; bacterial endotoxins test ; BSA ; bovine serum albumin ; DPBS ; Dulbecco's phosphate buffered saline ; ECVAM ; European Centre for the Validation of Alternative Methods ; EDQM ; European Directorate for the Quality of Medicines & Health Care ; ELISA ; enzyme-linked immunosorbent assay ; EU ; European Union ; GMP ; good manufacturing practice ; ICH ; International Conference on Harmonization ; IL-1尾 ; interleukin-1尾 ; IL-6 ; interleukin-6 ; MAT ; monocyte activation test ; NF魏B ; nuclear factor kappa B ; PBMCs ; p

刊名：Journal of Immunological Methods

出版年：March, 2014

作者：Chantra Eskes^a ; ^{chantra.eskes@secam-ce.eu} ; Vé ; ronique Detappe^b ; Herman Koë ; ter^c ; Joachim Kreysa^d ; Manfred Liebsch^e ; Valé ; rie Zuang^d ; Patric Amcoff^f ; Joã ; o Barroso^d ; José ; Cotovio^g ; Robert Guest^h ; Martina Hermannⁱ ; Sebastian Hoffmann^j ; Philippe Masson^k ; Nathalie Alé ; pé ; e^g ; Luis Alfonso Arce^l ; Beat Brü ; schweiler^m ; Tiziana Catoneⁿ ; Rostislav Cihak^o ; Jack Clouzeau^p ; Federica D’ ; Abrosca^q ; Cé ; dric Delveaux^r ; Jean Paul Derouette^s ; Oliver Engelking^t ; Davide Facchini^q ; Mirjam Frö ; hlicher^u ; Markus Hofmann^b ; Nancy Hopf^v ; Jennifer Molinari^w ; Aurelia Oberli^b ; Matthieu Ott^x ; Ronald Peter^b ; Vanessa M. Sá ; -Rocha^y ; Dominique Schenk^b ; Catherine Tomicic^b ; Philippe Vanparys^z ; Bernadette Verdon^aa ; Thomas Wallenhorst^ab ; Gian Christian Winkler^l ; Olivier Depallens^b

关键词：A.I.S.E ; International Association for Soaps ; Detergents and Maintenance products ; BfR ; German Federal Institute For Risk Assessment ; Cat ; category ; ECHA ; European Chemicals Agency ; ECVAM ; European Centre for the Validation of Alternative Methods ; ESAC ; E

刊名：Regulatory Toxicology and Pharmacology

出版年：2012

作者：Lakshmi Rajakrishna ; Salini Krishnan Unni ; Madhuri Subbiah ; Sathish Sadagopan ; Ayyappan R. Nair ; Ravindra Ch ; rappa ; Ganesh Sambasivam ; Sunil Kumar Sukumaran

关键词：In vitro genotoxicity screen ; Human cell based ; High-throughput ; p21 ; GADD153 ; p53 ; Reporter based screen ; ECVAM

刊名：Toxicology in Vitro

出版年：February, 2014

作者：Hongxia Chen^a ; ¹ ; Shuhua Li^c ; ¹ ; Tian Meng^a ; Lei Zhang^a ; Taoli Dai^a ; Qi Xiang^a ; ^b ; Zhijian Su^a ; ^b ; Qihao Zhang^a ; ^b ; ^{tqhzhang@jnu.edu.cn" class="auth_mail} ; Yadong Huang^a ; ^b ; ^{tydhuang@jnu.edu.cn" class="auth_mail}

关键词：Skin irritation ; Human skin ; Reconstructed organotypic skin model ; HSP27

刊名：Toxicology Letters

出版年：21 April, 2014

作者：U. Pfannenbecker^a ; ^{Uwe.Pfannenbecker@Beiersdorf.com} ; S. Bessou-Touya^b ; C. Faller^c ; ¹ ; J. Harbell^d ; T. Jacob^e ; H. Raabe^f ; M. Tailhardat^g ; N. Alé ; pé ; e^h ; A. De Smedtⁱ ; B. De Wever^j ; P. Jones^k ; Y. Kaluzhny^l ; B. Le Varlet^m ; P. McNameeⁿ ; M. Marrec-Fairley^o ; ² ; F. Van Goethemⁱ

关键词：ANOVA ; analysis of variance ; BCOP ; bovine corneal opacity and permeability test ; BLV ; between laboratory variability ; CE ; cosmetics Europe the personal care association ; ECVAM ; European centre for the validation of alternative methods ; EIT ; Eye Irritation

刊名：Toxicology in Vitro

出版年：2013