搜索页_+FaSSIF

设为首页

收藏本站

网站地图 | English | 公务邮箱

读者指南

学术客户端

NSTL服务站

科技查新

外文资源

Elsevier电子期刊(71)

在“Elsevier电子期刊”中，命中：71条，耗时：0.0309821 秒

在所有数据库中总计命中：71条

1.A novel microdialysis-dissolution/permeation system for testing oral dosage forms: A proof-of-concept study

作者：Sophia Yui Kau Fong ; Jessie Poulsen ; Martin Brandl ; Annette Bauer-Brandl ; ^{annette.bauer@sdu.dk}

关键词：D/P system ; dissolution/permeation system ; DSC ; differential scanning calorimetry ; FaSSIF ; fasted state simulated intestinal fluid ; HCS ; hydrocortisone ; IS ; internal standard ; Jss ; steady-state flux ; LLOD ; lower limit of detection ; LLOQ ; lower limit of quantification ; M-D/P system ; microdialysis-dissolution/permeation system ; MWCO ; molecular weight cut-off ; PBS ; phosphate buffer saline ; QC ; quality control ; RSD ; relative standard deviation ; UHPLC-UV ; Ultra-High-Performance Liquid Chromatography-

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

2.Dissolution behavior of co-amorphous amino acid-indomethacin mixtures: The ability of amino acids to stabilize the supersaturated state of indomethacin

作者：Rami Ojarinta^a ; ^{rami.ojarinta@uef.fi} ; Aki T. Heikkinen^b ; ^a ; Elina Sievä ; nen^c ; Riikka Laitinen^a

关键词：AA ; amino acid ; ACN ; acetonitrile ; ARG ; arginine ; AUC ; area under the curve ; CA ; co-amorphous ; DMSO ; dimethyl sulfoxide ; DS ; degree of supersaturation ; DSC ; differential scanning calorimetry ; EGF ; excipient gain factor ; FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; fed state simulated intestinal fluid ; FTIR ; Fourier transform infrared spectroscopy ; HPLC ; high performance liquid chromatography ; IND ; indomethacin ; PHE ; phenylalanine ; PM ; physical mixture ; SF ; supersaturation factor ; ssN

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

3.Theoretical Analysis of Drug Dissolution in Micellar Media

作者：Boris Shekunov ; ^{bshekunov@shire.com}

关键词：equilibrium solubility and intrinsic dissolution rate ; active pharmaceutical ingredients ; rotating disk apparatus ; drug particles ; diffusion and surface dissolution kinetics ; biologically relevant media ; FaSSIF ; FeSSIF ; micelles ; surfactants

刊名：Journal of Pharmaceutical Sciences

出版年：2017

4.Statistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugs

作者：Zhou Zhou ; Claire Dunn ; Ibrahim Khadra ; Clive G. Wilson ; Gavin W. Halbert ; ^{g.w.halbert@strath.ac.uk}

关键词：BCS ; Biopharmaceutics Classification System ; DoE ; Design of Experiment ; FASSIF ; Fasted Simulated Intestinal Fluid ; FESSIF ; Fed Simulated Intestinal Fluid ; IVIVC ; In vitro In vivo correlation

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

5.Evaluation of different in vitro dissolution tests based on level A in vitro-in vivo correlations for fenofibrate self-emulsifying lipid-based formulations

作者：Aude Pestieau^a ; ^{Aude.Pestieau@ulg.ac.be} ; Sonia Lebrun^b ; Bernard Cahay^b ; Adeline Brouwers^b ; Bruno Streel^b ; Jean-Michel Cardot^c ; Brigitte Evrard^a

关键词：Af ; absorbed API fraction without EHC ; API ; Active Pharmaceutical Ingredient ; AUC ; Area Under the Curve ; BCS ; Biopharmaceutics Classification System ; Cmax ; Maximal Concentration ; CS ; Saturation Concentration ; DSC ; Differential Scanning Calorimetry ; EHC ; EnteroHepatic Circulation ; EMA ; European Medicines Agency ; FaSSGF ; Fasted State Simulated Gastric Fluid ; FaSSIF ; Fasted State Simulated Intestinal Fluid ; FDA ; Food and Drug Administration ; FeSSIF ; Fed State Simulated Intestinal Fluid ; GIT ; Gastro

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2017

6.Comparison of 2 strategies to enhance pyridoclax solubility: Nanoemulsion delivery system versus salt synthesis

作者：A.-C. Groo ; M. De Pascale ; A.-S. Voisin-Chiret ; ^{anne-sophie.voisin@unicaen.fr} ; S. Corvaisier ; M. Since ; A. Malzert-Fré ; on ; ^{aurelie.malzert-freon@unicaen.fr}

关键词：Oligopyridine ; Nanoemulsions ; Solubility enhancement ; Biomimetic media ; Preclinical studies

刊名：European Journal of Pharmaceutical Sciences

出版年：2017

7.FaSSIF-V3, but not compendial media, appropriately detects differences in the peak and extent of exposure between reference and test formulations of ibuprofen

作者：Rodrigo Cristofoletti^a ; ^b ; Jennifer B. Dressman^b ; ^{dressman@em.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Dissolution ; Surface pH ; Biopharmaceutics Classification System (BCS) ; Capacity of detection ; Biowaiver

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

8.Does the commonly used pH-stat method with back titration really quantify the enzymatic digestibility of lipid drug delivery systems? A case study on solid lipid nanoparticles (SLN)

作者：Martha Heider^a ; ^{martha.heider@pharmazie.uni-halle.de} ; Gerd Hause^b ; ^{gerd.hause@biozentrum.uni-halle.de} ; Karsten Mä ; der^a ; ^{maeder@pharmazie.uni-halle.de}

关键词：CEH ; carboxyl ester hydrolase ; cmc ; critical micelle concentration ; CP ; cetyl palmitate ; FA ; fatty acids ; FaSSIF ; fasted state simulating medium ; FeSSIF ; fed state simulating medium ; GIT ; gastrointestinal tract ; HPTLC ; high performance thin layer chromatography ; LBDDS ; lipid based drug delivery systems ; P188 ; poloxamer 188 ; PDI ; polydispersity index ; PS80 ; polysorbate 80 ; SLN ; solid lipid nanoparticles

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

9.PLGA nanoparticles for peroral delivery: How important is pancreatic digestion and can we control it?

作者：Anika Mante¹ ; ² ; ^{anika.mante@medizin.uni-leipzig.de" class="auth_mail" title="E-mail the corresponding author} ; Martha Heider¹ ; ^{martha.heider@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author} ; Christin Zlomke ^{christin.zlomke@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author} ; Karsten Mä ; der ; ^{Maeder@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author}

关键词：FaSSIF ; fasted state simulated intestinal fluid ; FeSSIF ; simulated state intestinal fluid ; NPs ; nanoparticles ; PDI ; polydispersity index ; PEG-PLA ; pegylated poly(lactic acid) ; PLA ; poly(lactic acid) ; PLGA ; poly(lactideglycolic acid) ; PVA ; Poly(vinyl alcohol) ; Tris ; tris(hydroxymethyl)-aminomethan ; z-aver ; z-average

刊名：European Journal of Pharmaceutics and Biopharmaceutics

出版年：2016

10.Design, synthesis, and evaluation of novel porcupine inhibitors featuring a fused 3-ring system based on the ‘reversed’ amide scaffold

作者：Zhixiang Xu^a ; ^&dagger ; ; Xiangxiang Xu^a ; ^&dagger ; ; Ruadhan O&rsquo ; Laoi^b ; Haikuo Ma^a ; Jiyue Zheng^a ; ^{jyzheng@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Shuaishuai Chen^c ; Lusong Luo^c ; ^{lusong.luo@beigene.com" class="auth_mail" title="E-mail the corresponding author} ; Zhilin Hu^d ; Sudan He^d ; Jiajun Li^a ; Hongjian Zhang^a ; Xiaohu Zhang^a ; ^{xiaohuzhang@suda.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：BPO ; benzoyl peroxide ; DCM ; dichloromethane ; DIPEA ; N ; N-diisopropylethylamine ; DMF ; N ; N-dimethylformamide ; DMSO ; dimethyl sulfoxide ; FaSSIF ; fasted state simulated intestinal fluid ; HATU ; 1-[bis(dimethylamino)methylene]-1H-12 ; 3-triazolo[4 ; 5-b]pyridinium 3-oxid hexafluorophosphate ; SEM ; standard error measurement ; SGF ; simulated gastric fluid ; STF ; super-top flash ; TFA ; trifluoroacetic acid

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

按检索点细分(71)

题名(4)

关键词(32)

文摘(55)

按出版年细分(71)

2027年及以后(6)

2017年(6)

2016年(13)

2015年(1)

2013年(8)

2012年(6)

2011年(8)

2010年(3)

2009年(1)

2008年(3)

2007年(2)

2006年(2)

2005年(1)

2004年(1)

2003年(2)

2002年(1)

2000年(1)

2000年及以前(6)

常见问题　|　交通位置　|　联系我们　|　OA远程办公

地址：北京市海淀区学院路29号邮编：100083

电话：办公室：(+86 10)66554848；文献借阅、咨询服务、科技查新：66554700