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Elsevier电子期刊(164)

在“Elsevier电子期刊”中，命中：164条，耗时：0.1129425 秒

在所有数据库中总计命中：248条

1.High affinity binding of the peptide agonist TIP-39 to the parathyroid hormone 2 (PTH₂) receptor requires the hydroxyl group of Tyr-318 on transmembrane helix 5

作者：Richard E. Weaver^a ; Juan C. Mobarec^c ; Mark J. Wigglesworth^b ; ¹ ; Christopher A. Reynolds^c ; Dan Donnelly^a ; ^{d.donnelly@leeds.ac.uk}

关键词：Parathyroid hormone ; PTH ; GPCR ; Agonist ; Receptor ; TIP39

刊名：Biochemical Pharmacology

出版年：2017

2.Targeting calcium signaling in cancer therapy

作者：Chaochu Cui^a ; ^b ; Robert Merritt^b ; ^c ; Liwu Fu^a ; Zui Pan^b ; ^c ; ^d ; ^{zui.pan@uta.edu}

关键词：20-GPPD ; 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol ; CaM ; calmodulin ; CaMKII ; calmodulin-dependent protein kinase II ; CBD ; cannabidiol ; CBG ; cannabigerol ; CPZ ; capsazepine ; CRAC ; Ca2+ release-activated Ca2+ channel ; CTL ; cytotoxic T cells ; CYP3A4 ; cytochrome P450 3A4 ; ER/SR ; endoplasmic/sarcoplasmic reticulum ; HCX ; H+/Ca2+ exchangers ; IP3 ; inositol 14 ; 5-trisphosphate ; IP3R (1 ; 2 ; 3) ; IP3 receptor (type 1 ; type 2 ; type 3) ; mAb ; monoclonal antibody ; MCU ; mitochondrial Ca2+ uniporter ; MCUR1 ; MC

刊名：Acta Pharmaceutica Sinica B

出版年：2017

3.Elevated levels of alpha-synuclein blunt cellular signal transduction downstream of Gq protein-coupled receptors

作者：Mattia Volta ; ^{mattia.volta@eurac.edu} ; Alexandros A. Lavdas ; Julia Obergasteiger ; Christa Ü ; berbacher ; Anne Picard ; Peter P. Pramstaller ; Andrew A. Hicks ; Corrado Corti ; ^{corrado.corti@eurac.edu}

关键词：aSyn ; Alpha-synuclein ; PD ; Parkinson's disease ; PLCβ1 ; phospholipase Cβ1 ; PI(4 ; 5)P2 ; phosphoinositide-4 ; 5-bisphosphate ; Gq-PCRs ; Gq protein-coupled receptors ; IP3 ; inositol-14 ; 5-trisphosphate ; DAG ; diacylglycerol ; PKC ; protein kinase C ; MAPKs ; mitogen-activated protein kinase ; WT ; wild-type ; ERK1/2 ; extracellular-signal regulated kinase 1/2 ; 5-HT ; serotonin ; (CHO) ; Chinese hamster ovary cells ; FBS ; fetal bovine serum ; AP-1 ; activator protein-1 ; RT ; room temperature ; 5-HT ; serotonin ; SERCA ; sarc

刊名：Cellular Signalling

出版年：2017

4.Cell membrane modulation as adjuvant in cancer therapy

作者：Sara Zalba ; ^{s.zalbaoteiza@erasmusmc.nl} ; Timo L.M. ten Hagen

关键词：HMG-CoA reductase ; 3-hydroxy-methylglutaryl CoA reductase ; Emodin ; 3-methyl-16 ; 8-trihydroxyanthraquinone ; CL ; Cardiolipin ; Cer ; ceramide ; Ch ; cholesterol ; DAG ; Diacylglycerol ; ER ; endoplasmic reticulum ; EGFR ; epidermal growth factor receptor ; EGCG ; epigallocatechin gallate ; FADD ; Fas-Associated protein with Death Domain ; So ; gel solid-ordered state ; GCS ; Glucosylceramide synthase ; IP3 ; inositol 14 ; 5-triphosphate ; IGF-1 ; insulin-like receptor ; Ld ; liquid-disordered state ; Lo ; liquid-ordered sta

刊名：Cancer Treatment Reviews

出版年：2017

5.Ca^{2 +} microdomains, NAADP and type 1 ryanodine receptor in cell activation

作者：Andreas H. Guse ; ^{guse@uke.de" class="auth_mail" title="E-mail the corresponding author} ; Insa M.A. Wolf

关键词：ATP ; adenosine triphosphate ; ADPR ; adenosine diphosphoribose ; cADPR ; cyclic adenosine diphosphoribose ; ER ; endoplasmic reticulum ; IP3 ; d-myo-inositol 14 ; 5-trisphosphate ; IP3R ; d-myo-inositol 14 ; 5-trisphosphate receptor ; NAADP ; nicotinic acid adenine dinucleotide phosphate ; NAADP-BP ; NAADP binding protein ; NAD(P) ; nicotinamide adenine dinucleotide (phosphate) ; NFAT ; nuclear factor of T cells ; RyR ; ryanodine receptors ; RyR1 (or 2 ; or 3) ; type 1 (or 2 ; or 3) ryanodine receptor ; TRP-ML1 ; transient

刊名：Biochimica et Biophysica Acta (BBA)-Molecular Cell Research

出版年：2016

6.GPR40 agonists for the treatment of type 2 diabetes mellitus: The biological characteristics and the chemical space

作者：Cheng Chen^a ; ^b ; He Li^a ; Ya-Qiu Long^a ; ^{yqlong@simm.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：GPR40 ; G protein-coupled receptor 40 ; FFA1 ; free fatty acid receptor 1 ; PK ; pharmacokinetic ; GSIS ; glucose-stimulated insulin secretion ; T2DM ; type 2 diabetes mellitus ; IDF ; International Diabetes Federation ; GLP-1 ; glucagon-like peptide1 ; GIP ; gastric inhibitory polypeptide ; DPP4 ; dipeptidyl peptidase-4 ; LA ; linoleic acid ; DHA ; docosahexaenoic acid ; IP3 ; inositol-triphosphate 3 ; DAG ; diacylglycerol ; PA ; palmitic acid ; OA ; oleic acid ; MOE ; molecular operating environment ; CNS ; central nervous sy

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

7.Winning agonistic encounters increases testosterone and androgen receptor expression in Syrian hamsters

作者：Catherine T. Clinard ; ^{ctucke13@utk.edu" class="auth_mail" title="E-mail the corresponding author} ; Abigail K. Barnes ; Samuel G. Adler ; Matthew A. Cooper

关键词：CRH-R2 ; corticotropin-releasing hormone type-2 receptors ; dMeA ; dorsal medial amygdala ; LS ; lateral septum ; LSD ; least significant difference ; MeA ; medial amygdala ; MPOA ; medial preoptic area ; NGS ; normal goat serum ; PBS ; phosphate buffered saline ; PBS-GT ; phosphate buffered gelatin Triton ; PTH2R ; parathyroid hormone 2 receptor ; PTSD ; post-traumatic stress disorder ; TIP39 ; tuberoinfundibular peptide of 39 residues ; vLS ; ventral lateral septum ; vMeA ; ventral medial amygdala ; VMHL ; ventromedial hy

刊名：Hormones and Behavior

出版年：2016

8.Pyrazole antagonists of the CB1 receptor with reduced brain penetration

作者：Alan Fulp ; Yanan Zhang ; Katherine Bortoff ; Herbert Seltzman ; Rodney Snyder ; Robert Wiethe ; George Amato ; Rangan Maitra ; ^{rmaitra@rti.org" class="auth_mail" title="E-mail the corresponding author}

关键词：BBB ; blood&ndash ; brain barrier ; BOP ; benzotriazol-1-yl-oxytris(dimethylamino)phosphonium hexafluorophosphate ; CB ; cannabinoid receptors ; CB1 ; cannabinoid receptor 1 ; CB2 ; cannabinoid receptor 2 ; CHO-K1 ; Chinese hamster ovary cells ; CMA 80 ; 80% chloroform ; 18% methanol ; and 2% ammonium hydroxide ; CNS ; central nervous system ; Ke ; apparent affinity constant ; MDCK-mdr1 ; Madin&ndash ; Darby canine kidney cells transfected with the human MDR1 gene ; IP3 ; inositol phosphatase 3 ; MRM ; multiple reaction mon

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

9.The C-terminal region of Reelin is necessary for proper positioning of a subset of Purkinje cells in the postnatal cerebellum

作者：Kota Nakamura ; Mako Beppu ; Kaori Sakai ; Hayata Yagyu ; Saori Matsumaru ; Takao Kohno ; Mitsuharu Hattori ; ^{mhattori@phar.nagoya-cu.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：AP ; alkaline-phosphatase ; ApoER2 ; apolipoprotein E receptor 2 ; CTR ; C-terminal region ; EDTA ; ethylenediaminetetraacetic acid ; EGL ; external granule layer ; HEPES ; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid ; IP3R1 ; inositol 14 ; 5-trisphosphate receptor type 1 ; P ; postnatal day ; PBS ; phosphate-buffered saline ; PC ; Purkinje cells ; RR ; Reelin repeats ; SDS&ndash ; PAGE ; sodium dodecyl sulfate&ndash ; polyacrylamide gel electrophoresis ; VLDLR ; very low-density lipoprotein receptor ; WT ; wild-type ; Δ

刊名：Neuroscience

出版年：2016

10.“Tasting‿the cerebrospinal fluid: Another function of the choroid plexus?

作者：J. Tomás ; C.R.A. Santos ; T. Quintela ; I. Gonç ; alves ; ^{igoncalves@fcsaude.ubi.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：CNS ; central nervous system ; CP ; choroid plexus ; CPEC ; CP epithelial cells ; DMEM ; Dulbecco&rsquo ; s modified Eagle medium ; FBS ; fetal bovine serum ; GPCRs ; G protein-coupled receptors ; ICC ; immunocytochemistry ; IF ; immunofluorescence ; IHC ; immunohistochemistry ; IP3 ; inositol 14 ; 5-trisphosphate ; PBS ; phosphate-buffered saline ; Plcβ2 ; phospholipase C-beta 2 ; PROP ; 6-propyl-3-thiouracil ; PTC ; N-phenylthiourea ; RT ; room temperature ; T1R1 ; taste receptors type 1 ; T2R2 ; taste receptors type 2 ; TBS ; Tri

刊名：Neuroscience

出版年：2016

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