作者：Seyma Aydinlik ; MSc^a ; Merve Erkisa ; MSc^a ; Buse Cevatemre ; MSc^a ; Mehmet Sarimahmut ; PhD^a ; Egemen Dere ; PhD^a ; Ferda Ari ; PhD^a ; Engin Ulukaya ; MD^b ; ^{eulukaya@istinye.edu.tr}

关键词：TNBC ; triple negative breast cancer ; ROS ; reactive oxygen species ; H2DCFDA ; 2&prime ; 7&prime ; -dichlorodihydrofluorescein diacetate ; MTT ; 3-[4 ; 5-dimethyl-2-thiazolyl]-2 ; 5-diphenyl-2H-tetrazolium bromide ; CI value ; combination index value ; DXR ; doxorubicin ; 3-MA ; 3-methyladenine ; PI3K ; phosphoinositide 3-kinase ; PI ; propidium iodide ; Nec-1 ; necrostatin ; MLKL ; mixed lineage kinase domain-like ; RIPK1 ; receptor-TNFRSF-interacting serine threonine kinase1 ; TNFRSF10A ; Tumor necrosis factor receptor sup

刊名：Biochimica et Biophysica Acta (BBA) - General Subjects

出版年：2017

作者：Yanfang Xu^a ; ¹ ; ^{xuyanfang99@hotmail.com} ; Hua-bin Ma^b ; ¹ ; Yu-lu Fang^a ; Zhi-rong Zhang^b ; Jing Shao^b ; Mao Hong^b ; Chao-jun Huang^a ; Jing Liu^a ; Rui-qing Chen^c

关键词：RIP ; receptor-interacting protein ; MLKL ; mixed lineage kinase domain-like protein ; CypD ; cyclophilin-D ; ROS ; reactive oxygen species ; mPTP ; mitochondrial permeability transition pore ; TNFα ; tumor necrosis factor α ; CaMKII ; Ca2  ; +-calmodulin-dependent protein kinase II ; Nec-1 ; Necrostatin-1 ; BMDMs ; bone marrow-derived macrophages ; MAM ; mitochondria-associated membrane

刊名：Cellular Signalling

出版年：2017

作者：Siobhan M. Craige ; Michaella M. Reif ; Shashi Kant ; ^{shashi.kant@umassmed.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Signal transduction ; Kinase ; Inflammation ; Metabolism ; Insulin resistance ; Disease ; Mixed-lineage kinase

刊名：Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

出版年：2016

作者：Gang Zhang ; PhD^a ; ¹ ; Dongwei Guo ; MS^a ; ^b ; ¹ ; Prasanta K. Dash ; PhD^a ; ¹ ; Mariluz Araí ; nga ; DVM ; MSc ; PhD^a ; Jayme L. Wiederin ; MS^a ; ^c ; Nicole A. Haverland ; PhD^a ; ² ; Jaclyn Knibbe-Hollinger ; MPH^a ; Andrea Martinez-Skinner ; PhD^a ; Pawel Ciborowski ; PhD^a ; Val S. Goodfellow ; PhD^d ; Tadeusz A. Wysocki ; PhD^e ; Beata J. Wysocki ; PhD^e ; Larisa Y. Poluektova ; MD ; PhD^a ; Xin-Ming Liu ; PhD^a ; ^b ; ³ ; JoEllyn M. McMillan ; PhD^a ; Santhi Gorantla ; PhD^a ; Harris A. Gelbard ; MD ; PhD^f ; Howard E. Gendelman ; MD^a ; ^b ; ^{hegendel@unmc.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：HIV-1 ; Long-acting nanoformulations ; URMC-099 ; Humanized mice ; Phagolysosome ; Rab proteins

刊名：Nanomedicine: Nanotechnology, Biology and Medicine

出版年：2016

作者：Manuel Wallbach^a ; ¹ ; ² ; Jorge Duque Escobar^b ; ¹ ; Rohollah Babaeikelishomi^a ; ^b ; ¹ ; ³ ; Marie-Jeannette Stahnke^a ; Roland Blume^a ; Sabine Schrö ; der^b ; Jenny Kruegel^c ; Kathrin Maedler^d ; Oliver Kluth^e ; Ralph H. Kehlenbach^f ; Nicolai Miosge^c ; Elke Oetjen^a ; ^b ; ^g ; ^{e.oetjen@uke.uni-hamburg.de" class="auth_mail" title="E-mail the corresponding author}

关键词：CBP ; CREB binding protein ; CRE ; cAMP responsive element ; CREB ; CRE binding protein ; CRTC ; cAMP regulated transcriptional coactivator ; DLK ; Dual leucine zipper kinase ; IL-1β ; Interleukin-1β ; JIP/IB-1 ; JNK interacting protein/islet-brain-1 ; JNK ; c-Jun N-terminal kinase ; LZK ; Leucine zipper kinase ; MAPK ; Mitogen-activated protein kinase ; MBP ; Maltose binding protein ; MLK ; Mixed lineage kinase ; NES ; Nuclear export signal ; NLS ; Nuclear localization signal ; TNFα ; Tumor necrosis factor α

刊名：Cellular Signalling

出版年：2016

作者：Yi Qu^a ; ^b ; ¹ ; ^{quyi712002@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jing Shi^a ; ^b ; ¹ ; Ying Tang^a ; ^b ; Fengyan Zhao^a ; ^b ; Shiping Li^a ; ^b ; Junjie Meng^a ; ^b ; Jun Tang^a ; ^b ; Xuemei Lin^b ; Xiaodong Peng^c ; Dezhi Mu^a ; ^b ; ^d ; ^{dezhi.mu@ucsf.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ANOVA ; analysis of variance ; BHA ; butylated hydroxyanisole ; CCA ; common carotid artery ; Drp1 ; dynamin-related protein-1 ; HI ; hypoxia-ischemia ; MLKL ; mixed lineage kinase domain-like protein ; NAC ; N-acetylcysteine ; Nec-1 ; necrostatin 1 ; NSS ; neurological severity score ; OGD ; oxygen-glucose deprivation ; PGAM5 ; phosphoglycerate mutase family member 5 ; RIP1 ; receptor interacting protein kinase 1 ; RIP3 ; receptor interacting protein kinase 3 ; ROS ; reactive oxygen species ; SD ; Sprague&ndash ; Dawley ; TRP

刊名：Experimental Neurology

出版年：2016

作者：Xiao-Hui Yin^a ; ^{yinxiaohui2013@163.com" class="auth_mail" title="E-mail the corresponding author} ; Jing-Zhi Yan^a ; Guo Yang^a ; Li Chen^a ; Xiao-Feng Xu^a ; Xi-Ping Hong^a ; Shi-Liang Wu^b ; ; Xiao-Yu Hou^a ; ^{xyhou@xzmc.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; GuangYi Zhang^a ; ^&dagger ;

关键词：PSD-95 ; Postsynaptic density protein 95 ; MLK3 ; Mixed Lineage Kinase 3 ; JNK ; c-Jun N-terminal kinase ; FADD ; Fas associated death domain protein ; DISC ; death-inducing signaling complex

刊名：Brain Research

出版年：2016

作者：Xue Wen Wei^a ; ^b ; ¹ ; Ling Yun Hao^a ; ^c ; ¹ ; Su Hua Qi^a ; ^{qisuhua9999@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：eNOS ; endothelial nitric oxide synthase ; GSNO ; S-nitrosoglutathione ; iNOS ; inducible nitric oxide synthase ; I/R ; ischemia/reperfusion ; JNK ; c-Jun NH2-terminal kinase ; MAPK ; mitogen-activated protein kinase ; MKK4 ; mitogen-activated protein kinase kinase 4 ; MLK3 ; mixed-lineage kinase 3 ; MK-801 ; dizocilpine hydrogen maleate ; NMDAR ; N-methyl-d-aspartate receptor ; nNOS ; neuronal nitric oxide synthase ; NO ; nitric oxide ; NOS ; nitric oxide synthase ; PSD-95 ; postsynaptic density protein-95 ; SDS-PAGE ; sod

刊名：Brain Research Bulletin

出版年：2016

作者：Rebecca L. McCullough^a ; Megan R. McMullen^a ; Dola Das^a ; Sanjoy Roychowdhury^a ; Michael G. Strainic^b ; M. Edward Medof^b ; Laura E. Nagy^a ; ^c ; ^{nagyL3@ccf.org" class="auth_mail" title="E-mail the corresponding author}

关键词：4-HNE ; 4-hydroxy-2-nonenal ; ALD ; alcoholic liver disease ; ALT ; alanine aminotransferase ; C5aR ; C5a Receptor ; CCl4 ; carbon tetrachloride ; CK18 ; cytokeratin18 ; CYP2E1 ; cytochrome P450 2E1 ; IL-6 ; interleukin-6 ; MCP-1 ; macrophage chemoattractant protein-1 ; mRNA ; messenger RNA ; MLKL ; mixed lineage kinase domain-like ; RIP ; receptor-interacting protein kinase ; ROS ; reactive oxygen species ; TG ; triglyceride ; TNFα ; tumor necrosis factor-α

刊名：Molecular Immunology

出版年：2016

作者：Kenji Mizumura ; MD ; PhD^a ; ^{mizumura.kenji@nihon-u.ac.jp} ; Shuichiro Maruoka ; MD ; PhD^a ; ^{maruoka.shuichiro@nihon-u.ac.jp} ; Yasuhiro Gon ; MD ; PhD^a ; ^{gon.yasuhiro@nihon-u.ac.jp} ; Augustine M.K. Choi ; MD^b ; ^{amc2056@med.cornell.edu} ; Shu Hashimoto ; MD ; PhD^a ; ^{hashimoto.shu@nihon-u.ac.jp}

关键词：Necroptosis ; Autophagy ; Mitophagy ; Chronic obstructive pulmonary disease

刊名：Respiratory Investigation

出版年：2016