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在“Elsevier电子期刊”中，命中：604条，耗时：0.0629695 秒

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1.Network pharmacology-based study on the mechanism of action for herbal medicines in Alzheimer treatment

作者：Jiansong Fang^a ; ^b ; Ling Wang^c ; Tian Wu^a ; ^b ; Cong Yang^a ; ^b ; Li Gao^d ; Haobin Cai^a ; ^b ; Junhui Liu^e ; Shuhuan Fang^a ; ^b ; Yunbo Chen^a ; ^b ; Wen Tan^f ; ^{went@scut.edu.cn} ; Qi Wang^a ; ^b ; ^{wqitcm@qq.com}

关键词：AD ; Alzheimer's disease ; NFT ; neurofibrillary tangles ; ChE ; cholinesterase ; NMDA ; N-methyl-D-aspartate ; TCM ; Traditional Chinese Medicine ; MOA ; mechanisms of action ; TCMSP ; traditional Chinese medicine systems pharmacology ; TCMID ; traditional Chinese medicine integrative database ; MW ; molecular weight ; HBAs ; the number of H acceptors ; HBDs ; the number of H donors ; logPo/w ; Log octanol/water partition coefficient ; b_rotN ; the number of rotable bonds ; TPSA ; topological polar surface area ; logS ; Lo

刊名：Journal of Ethnopharmacology

出版年：2017

2.Pharmacological response sensitization in nerve cell networks exposed to the antibiotic gentamicin

作者：Kevin S. Hamilton^a ; ^c ; ^{kevinhamilton2@my.unt.edu} ; Kamakshi V. Gopal^a ; ^c ; ^{Gopal@unt.edu} ; Ernest J. Moore^a ; ^c ; ^{Ernest.Moore@unt.edu} ; Guenter W. Gross^b ; ^c ; ^{Guenter.Gross@unt.edu}

关键词：In vitro ; Neural networks ; Gentamicin ; GABA ; Muscimol ; Sensitization

刊名：European Journal of Pharmacology

出版年：2017

3.Network Pharmacology-based Approaches Capture Essence of Chinese Herbal Medicines

作者：Yan-qiong Zhang^a ; Xia Mao^a ; Qiu-yan Guo^a ; Na Lin^a ; Shao Li^b ; ^{shaoli@mail.tsinghua.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：bioactive ingredient ; Chinese herbal medicine ; molecular mechanism ; network pharmacology ; network target

刊名：Chinese Herbal Medicines

出版年：2016

4.Decrease of high voltage Ca²⁺ currents in the dentate gyrus granule cells by entorhinal amyloidopathy is reversed by calcium channel blockade

作者：Hamid Gholami Pourbadie^a ; ^b ; ^c ; Nima Naderi^b ; ^d ; Hadi Mirzapour Delavar^a ; Mahshid Hosseinzadeh^b ; Nasrin Mehranfard^b ; ^c ; Fariba Khodagholi^b ; Mahyar Janahmadi^e ; Fereshteh Motamedi^b ; ^c ; ^{motamedi@ams.ac.ir}

关键词：Calcium ; Alzheimer ; Amyloid ; Dentate gyrus ; Calbindin

刊名：European Journal of Pharmacology

出版年：2017

5.Drug discovery of neurodegenerative disease through network pharmacology approach in herbs

作者：Zhipeng Ke^a ; Xinzhuang Zhang^a ; Zeyu Cao^a ; Yue Ding^a ; Na Li^a ; Liang Cao^a ; Tuanjie Wang^a ; Chenfeng Zhang^a ; Gang Ding^a ; Zhenzhong Wang^a ; Xiaojie Xu^b ; ^{xiaojxu@pku.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Wei Xiao^a ; ^{xw_kanion@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Neurodegenerative diseases ; Network pharmacology ; Drug discovery ; Virtual screening

刊名：Biomedicine & Pharmacotherapy

出版年：2016

6.Network pharmacology of cancer: From understanding of complex interactomes to the design of multi-target specific therapeutics from nature

作者：Paramasivan Poornima^a ; ¹ ; Jothi Dinesh Kumar^b ; ¹ ; Qiaoli Zhao^c ; Martina Blunder^d ; Thomas Efferth^c ; ^{efferth@uni-mainz.de" class="auth_mail" title="E-mail the corresponding author}

关键词：Eleutherococcus senticosus ; Genomics ; Green tea polyphenolics ; Lithospermum erythrorhizon ; Metabolomics ; Polypharmacology ; Proteomics ; Rhodiola rosea ; Schisandra chinensis ; Synthetic lethality ; Systems biology ; Transcriptomics

刊名：Pharmacological Research

出版年：2016

7.Combination of Astragalus membranaceus and Euonymus alatus (THUNB.) SIEB. for treatment of diabetes: A network-based pharmacology research

作者：Kun Chen^a ; ¹ ; Dong Deng^a ; ¹ ; Youliang Huang^a ; ¹ ; Xiaoyun Ma^a ; Xueli Li^a ; Wenting Zhang^a ; Zhiyong Li^b ; Yang Liu^a ; Wei Wang^a ; Jianxin Chen^a ; ^{cjx@bucm.edu.cn} ; HuiHui Zhao^a ; ^{zhaohh@bucm.edu.cn}

关键词：Astragalus ; Euonymus alatus ; Diabetes ; ESR1 ; REN

刊名：Journal of Traditional Chinese Medical Sciences

出版年：2016

8.Systems pharmacology - Towards the modeling of network interactions

作者：Meindert Danhof ^{m.danhof@lacdr.leidenuniv.nl" class="auth_mail" title="E-mail the corresponding author}

关键词：Adaptive systems ; Non-adaptive systems ; Hysteresis ; Variability ; Non-linearity ; Interdependency ; Convergence ; Resilience ; Multi-stationarity ; Synergy ; Oscillation ; Disease progression

刊名：European Journal of Pharmaceutical Sciences

出版年：2016

9.A systems pharmacology approach to decipher the mechanism of danggui-shaoyao-san decoction for the treatment of neurodegenerative diseases

作者：Yunxia Luo^a ; Qi Wang^b ; ^{wqitcm@qq.com" class="auth_mail" title="E-mail the corresponding author} ; Yongbin Zhang^a ; ^{yongbinzhang@gzucm.edu.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：DSS ; danggui-shaoyao-san ; NDs ; neurodegenerative diseases ; TCM ; traditional Chinese medicine ; AD ; Alzheimer's disease ; PD ; Parkinson's disease ; HD ; Huntington's disease ; ALS ; amyotrophic lateral sclerosis ; AIA ; aspirin-intolerant asthma ; PRA ; Paeoniae Radix Alba ; ASR ; Angelica Sinensis Radix ; CR ; Chuanxiong Rhizoma ; P ; Poria ; AMR ; Atractylodis Macrocephalae Rhizoma ; AR ; Alismatis Rhizoma ; TCMSP ; the traditional Chinese medicine systems pharmacology database and analysis platform ; OB ; oral bioava

刊名：Journal of Ethnopharmacology

出版年：2016

10.Systematic network assessment of the carcinogenic activities of cadmium

作者：Peizhan Chen^a ; ¹ ; Xiaohua Duan^a ; ¹ ; Mian Li^a ; Chao Huang^a ; Jingquan Li^a ; ^b ; Ruiai Chu^a ; ^b ; Hao Ying^a ; ^b ; Haiyun Song^a ; ^b ; Xudong Jia^b ; Qian Ba^a ; ^b ; ^{qba@sibs.ac.cn" class="auth_mail" title="E-mail the corresponding author} ; Hui Wang^a ; ^b ; ^c ; ^{huiwang@sibs.ac.cn" class="auth_mail" title="E-mail the corresponding author}

关键词：Cadmium ; Carcinogenesis ; Network assessment

刊名：Toxicology and Applied Pharmacology

出版年：2016

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