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在“Elsevier电子期刊”中，命中：65条，耗时：0.0309803 秒

在所有数据库中总计命中：226条

1.Digital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal cancer patients

作者：Andrea Sartore-Bianchi^a ; Filippo Pietrantonio^b ; Alessio Amatu^a ; Massimo Milione^c ; Andrea Cassingena^a ; Silvia Ghezzi^a ; Marta Caporale^b ; Rosa Berenato^b ; Chiara Falcomatà ; ^d ; ^e ; Alessio Pellegrinelli^c ; Alberto Bardelli^d ; ^e ; Michele Nichelatti^a ; Federica Tosi^a ; Filippo De Braud^b ; Federica Di Nicolantonio^d ; ^e ; Ludovic Barault^d ; ^e ; ¹ ; ^{ludovic.barault@unito.it} ; Salvatore Siena^a ; ^f ; ¹

关键词：MGMT ; Immunohistochemistry ; DNA methylation ; Digital PCR ; Metastatic colorectal cancer ; Alkylating agent

刊名：European Journal of Cancer

出版年：2017

2.Permeability Surface Area Product Using Perfusion Computed Tomography Is a Valuable Prognostic Factor in Glioblastomas Treated with Radiotherapy Plus Concomitant and Adjuvant Temozolomide

作者：Taiichi Saito¹ ; ^{taiichis@gmail.com} ; Kazuhiko Sugiyama² ; Fusao Ikawa¹ ; Fumiyuki Yamasaki¹ ; Minoru Ishifuro³ ; Takeshi Takayasu¹ ; Ryo Nosaka¹ ; Ikuno Nishibuchi⁴ ; Yoshihiro Muragaki⁵ ; Takakazu Kawamata⁵ ; Kaoru Kurisu¹

关键词：Glioblastoma ; Perfusion CT ; Permeability surface area product ; Temozolomide

刊名：World Neurosurgery

出版年：2017

3.Immunohistochemical analysis of O6-methylguanine-DNA methyltransferase (MGMT) protein expression as prognostic marker in glioblastoma patients treated with radiation therapy with concomitant and adjuvant Temozolomide

作者：Samar Galal Younis^a ; Rasha Abd El-Ghany Khedr^a ; ^{Khedr_rasha@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Safinaz Hamdy El-Shorbagy^b

关键词：O6-methylguanine-DNA methyltransferase ; Glioblastoma ; Temozolomide ; Immunohistochemistry

刊名：Journal of the Egyptian National Cancer Institute

出版年：2016

4.Detection of O6-methylguanine-DNA methyltransferase gene promoter region methylation pattern using pyrosequencing and the effect of methylation pattern on survival, recurrence, and chemotherapy sensitivity in patients with laryngeal cancer

作者：Ozlem Onerci Celebi^a ; ^{oonerci@yahoo.com" class="auth_mail" title="E-mail the corresponding author} ; Gaye Guler Tezel^b ; Ali Sefik Hosal^a ; Mustafa Cengiz^c ; Ibrahim Halil Gullu^d ; Mutlu Hayran^e

关键词：Laryngeal cancer ; O6-methylguanine-DNA methyltransferase methylation ; Pyrosequencing ; Chemotherapy sensitivity ; Survival

刊名：Pathology - Research and Practice

出版年：2016

5.Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment

作者：Jun-Hai Tang^a ; Zhi-Xiong Ma^b ; Guo-Hao Huang^a ; Qing-Fu Xu^a ; Yan Xiang^a ; Ningning Li^c ; Kastytis Sidlauskas^c ; Eric Erquan Zhang^b ; Sheng-Qing Lv^a ; ^{lvsq0518@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：TMZ ; temozolomide ; HIF-1α ; hypoxia inducible factor 1α ; MTT ; 3-(4 ; 5-cimethylthiazol-2-yl)-2 ; 5-diphenyl tetrazolium bromide ; MGMT ; O6-methylguanine DNA methyltransferase ; PFS ; progression-free-survival ; GBM ; glioblastoma multiforme ; HREs ; hypoxia response elements ; CSCs ; cancer stem cells ; GSCs ; glioblastoma stem cells ; NSCs ; neural stem cells ; NICD ; Notch1 intracelluar domain ; EMT ; epithelial-mesenchymal transition ; BBB ; blood brain barrier ; O6-MG ; O6-methylated guanine ; MMR ; mismatch repair ; 2M

刊名：Experimental Cell Research

出版年：2016

6.Heterogeneity of Cancer Stem Cells: Rationale for Targeting the Stem Cell Niche

作者：Maximilian Boesch^a ; ^b ; ^c ; ¹ ; ^{Maximilian.Boesch@kssg.ch} ; Sieghart Sopper^b ; ^c ; ¹ ; ^{Sieghart.Sopper@i-med.ac.at} ; Alain G. Zeimet^d ; ^{Alain.Zeimet@i-med.ac.at} ; Daniel Reimer^d ; ^{Daniel.Reimer@i-med.ac.at} ; Guenther Gastl^b ; ^{Guenther.Gastl@i-med.ac.at} ; Burkhard Ludewig^a ; ^{Burkhard.Ludewig@kssg.ch} ; Dominik Wolf^b ; ^c ; ^e ; ^{Dominik.Wolf@ukb.uni-bonn.de}

关键词：ABC ; ATP-binding cassette ; ALDH ; aldehyde dehydrogenase ; CAF ; cancer-associated fibroblast ; CSC ; cancer stem cell ; EMT ; epithelial-to-mesenchymal transition ; FACS ; fluorescence-activated cell sorting ; LSC ; leukemic stem cell ; mAb ; monoclonal antibody ; MGMT ; O(6)-methylguanine-DNA-methyltransferase ; MRD ; minimal residual disease ; SP ; side population ; TKI ; tyrosine kinase inhibitor ; TME ; tumor microenvironment ; TSC ; tissue stem cell

刊名：Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

出版年：2016

7.Guidelines, “minimal requirements” and standard of care in glioblastoma around the Mediterranean Area: A report from the AROME (Association of Radiotherapy and Oncology of the Mediterranean arEa) Neuro-Oncology working party

作者： On behalf of AROME French Panel by alphabetic orderY. Belkacemi ; ^{yazid.belkacemi@hmn.aphp.fr" class="auth_mail" title="E-mail the corresponding author} ; S. Bolle ; F. Bourdeaut ; P. Collin ; P. Cornu ; J.-Y. Delatre ; F. Dhermain ; F. Doz ; J.-L. Habrand ; K. Hoang-Xuan ; A. Idbaih ; H. Mammar ; N. Martin-Duverneuil ; K. Mokhtari ; T. Roujeau

关键词：OS ; overall survival ; PFS ; progression-free survival ; WHO ; World Health Organization ; MA ; Mediterranean area ; AROME ; association of radiotherapy and oncology of the Mediterranean area ; MTDs ; multidisciplinary teams meetings ; MRI ; magnetic resonance imaging ; DWI ; diffusion weighted imaging ; MRS ; magnetic resonance spectroscopy ; TMZ ; temozolomide ; KPS ; Karnofsky prognostic index ; MGMT ; Methylation of the O6-methylguanine-DNA methyltransferase ; RTOG ; Radiation Therapy Oncology Group ; EBRT ; external

刊名：Critical Reviews in Oncology and Hematology

出版年：2016

8.Temozolomide analogs with improved brain/plasma ratios - Exploring the possibility of enhancing the therapeutic index of temozolomide

作者：Roopa Rai^a ; ; Monali Banerjee^b ; Darren H. Wong^c ; Emma McCullagh^a ; ; Ashu Gupta^d ; Shailendra Tripathi^d ; Eduardo Riquelme^e ; Ramnivas Jangir^d ; Shyamraj Yadav^d ; Mohd. Raja^d ; Pankaj Melkani^d ; Vikas Dixit^d ; Umesh Patil^d ; Ritesh Shrivastava^b ; Sandip Middya^b ; Felipe Olivares^e ; Javier Guerrero^e ; Arjun Surya^b ; Son M. Pham^a ; Sebastiá ; n Bernales^a ; Andrew A. Protter^a ; David T. Hung^a ; Sarvajit Chakravarty^a

关键词：Temozolomide ; Glioblastoma ; Chemotheraphy ; O6-Methyl-2&prime ; -deoxyguanosine (O6-MedG)

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

9.Impact of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and MGMT expression on dacarbazine resistance of Hodgkin's lymphoma cells

作者：Stefanie Kewitz ; Martina Stiefel ; Christof M. Kramm ; Martin S. Staege

关键词：Hodgkin's lymphoma ; Dacarbazine ; O6-methylguanine-DNA methyltransferase ; Promoter methylation

刊名：Leukemia Research

出版年：January, 2014

10.Target-mediated consecutive endonuclease reactions for specific and sensitive homogeneous fluorescence assay of O⁶-methylguanine-DNA methyltransferase

作者：Dinh-Vu Le ; Dian-Ming Zhou ; Li-Juan Tang ; Jian-Hui Jiang ; Ru-Qin Yu ; Yu-Zhi Wang

关键词：O6-Methylguanine DNA methyltransferase ; DNA-repair enzyme ; Alkyltransferase ; Restriction endonuclease ; Fluorescence

刊名：Analytica Chimica Acta

出版年：4 December, 2013

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