作者：Da-Gang Zhang^a ; ¹ ; Cheng Zhang^b ; ¹ ; Jun-Xian Wang^a ; Bi-Wei Wang^b ; Hua Wang^b ; Zhi-Hui Zhang^b ; Yuan-Hua Chen^b ; Yan Lu^c ; Li Tao^c ; Jian-Qing Wang^c ; Xi Chen^a ; ; De-Xiang Xu^b ; ^{xudex@126.com}

关键词：CCl4 ; carbon tetrachloride ; CDCA ; chenodeoxycholic acid ; ERK ; extracellular regulated protein kinase ; FXR ; farnesoid X receptor ; IkB ; inhibitor of kB ; IL ; interleukin ; KC ; keratinocyte-derived chemokine ; MAPK ; mitogen-activated protein kinase ; MCP-1 ; monocyte chemotactic protein 1 ; MIP ; macrophage inflammatory protein ; NF-κB ; nuclear factor kappa B ; OCA ; obeticholic acid ; TNF-α ; tumor necrosis factor alpha ; TUNEL ; terminal dUTP nick-end labeling ; UDCA ; ursodeoxycholic acid

刊名：Toxicology and Applied Pharmacology

出版年：2017

作者：Fabiola M. Ribeiro^a ; Luciene B. Vieira^b ; Rita G.W. Pires^c ; Roenick P. Olmo^a ; Stephen S.G. Ferguson^d ; ^{sferguso@uottawa.ca}

关键词：AMPA ; α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid ; Aβ ; amyloid β peptide ; AD ; Alzheimer&rsquo ; s disease ; APP ; amyloid precursor protein ; BDNF ; brain derived neurotrophic factor ; BF ; basal forebrain ; CGA ; chromogranin A ; CNS ; central nervous system ; DAG ; diacylghycerol ; ERK ; extracellular signal-regulated kinase ; GABA ; gamma-aminobutyric acid ; GDNF ; glial cell line-derived neurotrophic factor ; GIRK ; inward rectifying K+ channels ; GP ; globus pallidum ; GPe ; globus pallidum externa ; GPCR ; G

刊名：Pharmacological Research

出版年：2017

作者：Sai Vikram Vemula^a ; Jill W. Maxwell^a ; Alexey Nefedov^b ; Bang-Lin Wan^d ; Justin Steve^d ; William Newhard^a ; Rosa I. Sanchez^d ; David Tellers^c ; Richard J. Barnard^a ; Wade Blair^a ; Daria Hazuda^a ; Andrea L. Webber^b ; Bonnie J. Howell^a ; ^{bonnie_howell@merck.com}

关键词：HIV latency ; Protein kinase C agonists ; Biomarkers

刊名：Antiviral Research

出版年：2017

作者：Richard J. Bodnar ^{richard.bodnar@qc.cuny.edu}

关键词：Ach ; acetylcholine ; ACL ; anterior cruciate ligament ; ACTH ; adrenocorticotrophic hormone ; AMP ; adenosine monophosphate ; AMPK ; 5&prime ; adenosine monophosphate-activated protein kinase ; AS ODN ; antisense oligonucleotide ; BDNF ; brain-derived neurotrophic factor ; BEND ; beta-endorphin ; BFNA ; beta-funaltrexamine ; BNST ; bed nucleus of the stria terminalis ; Ca(2+) ; calcium ; CART ; cocaine and amphetamine-regulated transcript ; CB ; cannabinoid ; CCK ; cholecystokinin ; CFA ; complete Freund&rsquo ; s adjuvant ; Ch

刊名：Peptides

出版年：2017

作者：Maria C. Olianas ; ^{molianas@unica.it} ; Simona Dedoni ; Pierluigi Onali

关键词：CGP7930 (PubChem CID ; 5024764) ; GS39783 (PubChem CID ; 6604928) ; (-)-baclofen (PubChem CID ; 44602) ; SKF97541 (PubChem CID ; 5230) ; CGP55845 (PubChem CID ; 5311042) ; CGP54626 (PubChem CID ; 197584) ; phorbol 12-myristate 13 acetate (PubChem CID ; 27924) ; Go 6850 (PubChem CID ; 2396) ; 5Z-7-oxozeaenol (PubChem CID ; 9863776) ; GW5074 (PubChem CID ; 5924208)

刊名：European Journal of Pharmacology

出版年：2017

作者：Rosa M. Andr&eacute ; s¹ ; ² ; Mar&iacute ; a Carmen Terencio¹ ; ² ; Jorge Arasa¹ ; ² ; Miguel Pay&aacute ; ¹ ; ² ; Francisca Valcuende-Cavero³ ; ⁴ ; Pedro Naval&oacute ; n⁵ ; Mar&iacute ; a Carmen Montesinos¹ ; ² ; ^{m.carmen.montesinos@uv.es}

关键词：AR ; adenosine receptors ; BAY ; BAY60&ndash ; 6583 ; CGS ; CGS-21680 ; iCa2+ ; intracellular calcium ; MRS ; MRS-1706 ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; NECA ; 5'-N-ethylcarboxamidoadenosine ; NHEK ; normal human epidermal keratinocyte ; SCH ; SCH-442416 ; TNF ; tumor necrosis factor ; TPA ; 12-O-tetradecanoylphorbol-13-acetate

刊名：Journal of Investigative Dermatology

出版年：2017

作者：Nicole M. Jackson ; Brian P. Ceresa ; ^{brian.ceresa@louisville.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Epidermal Growth Factor Receptor ; Protein Kinase G ; Apoptosis ; MDA-MB-468 cells

刊名：Experimental Cell Research

出版年：2016

作者：Jonathan Scott ; MPhil^a ; Graham J. Harris ; MBBS ; MRes^a ; Emma M. Pinder ; MRCP(UK)^a ; James G. Macfarlane ; MRCP(UK)^a ; Thomas P. Hellyer ; MRCP(UK)^a ; Anthony J. Rostron ; PhD ; FRCP^a ; Andrew Conway Morris ; PhD ; FRCA^b ; David R. Thickett ; DM ; FRCP^c ; Gavin D. Perkins ; MD ; FRCP^d ; Daniel F. McAuley ; MD ; FRCP^e ; ^f ; John D. Widdrington ; MBBS ; MRes^a ; Sarah Wiscombe ; MBChB^a ; Simon V. Baudouin ; MD ; FRCP^g ; Alistair I. Roy ; FFICM^h ; Vanessa C. Linnett ; FRCAⁱ ; Stephen E. Wright ; FRCA^j ; Marie-H&eacute ; lè ; ne Ruchaud-Sparagano ; PhD^a ; A. John Simpson ; PhD ; FRCP(Edin)^a ; ^{j.simpson@ncl.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Neutrophil ; β2-agonist ; cyclic AMP ; exchange protein directly activated by cyclic AMP ; hospital-acquired infection

刊名：Journal of Allergy and Clinical Immunology

出版年：2016

作者：Lisa A. Stott^a ; David A. Hall^b ; Nicholas D. Holliday^a ; ^{nicholas.holliday@nottingham.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：CRC ; concentration response curve ; EC50 ; effective agonist concentration for 50% maximum response ; Emax ; maximum system response ; GPCR ; G protein coupled receptor ; D2R ; dopamine D2 receptor ; GTPγS ; guanosine 5&prime ; -O-[γ-thio]triphosphate ; KA ; agonist equilibrium dissociation constant ; KE ; concentration of agonist&ndash ; receptor complex which produces a half maximal effect ; MAPK ; mitogen activated protein kinase ; RAi ; relative intrinsic activity ratio ; Rmax ; maximum agonist response ; RT ; total

刊名：Biochemical Pharmacology

出版年：2016

作者：Andrea Cu&iacute ; ñ ; as ; Ver&oacute ; nica Garc&iacute ; a-Morales ; Dolores Viña ; Jos&eacute ; Gil-Longo ; Manuel Campos-Toimil ; ^{manuel.campos@usc.es" class="auth_mail" title="E-mail the corresponding author}

关键词：AVP ; arginine-vasopressin ; [Ca2  ; +]c ; cytoplasmic Ca2  ; + concentration ; cAMP ; 3&prime ; 5&prime ; -cyclic adenosine monophosphate ; db-cAMP ; dibutyryl cyclic AMP ; DMSO ; dimethyl sulfoxide ; Epac ; exchange protein directly activated by cAMP ; FBS ; foetal bovine serum ; KBS ; Krebs bicarbonate solution ; PKA ; cyclic-AMP protein kinase ; RASMC ; rat aortic smooth muscle cells ; SERCA ; sarcoplasmic/endoplasmic reticulum Ca2  ; +-ATPase ; SOCE ; store-operated Ca2  ; + entry ; VOCC ; voltage-operated Ca2

刊名：Life Sciences

出版年：2016